{ "responseHeader":{ "status":0, "QTime":0, "params":{ "q":"iati_identifier:GB-GOV-10-NIHR_GHRU2", "fl":"*", "format":"json" } }, "response":{ "numFound":1, "start":0, "numFoundExact":true, "docs":[{ "default-currency":"GBP", "default_currency":"GBP", "hierarchy":1, "humanitarian":false, "last-updated-datetime":"2026-03-25T11:12:22.540Z", "last_updated_datetime":"Wed Mar 25 11:12:22 UTC 2026", "last_updated_datetime_f":"2026-03-25T11:12:22.540Z", "lang":"en", "default_lang":"en", "iati-identifier":"GB-GOV-10-NIHR_GHRU2", "iati_identifier":"GB-GOV-10-NIHR_GHRU2", "reporting-org.ref":"GB-GOV-10", "reporting_org_ref":"GB-GOV-10", "reporting-org.type":"10", "reporting_org_type_code":"10", "reporting-org.narrative":["UK - Department of Health and Social Care (DHSC)"], "reporting_org_narrative":["UK - Department of Health and Social Care (DHSC)"], "reporting-org.narrative.lang":[" "], "title.narrative":["NIHR Global Health Research Units: Call 2"], "title_narrative":["NIHR Global Health Research Units: Call 2"], "title_narrative_text":["NIHR Global Health Research Units: Call 2"], "title.narrative.lang":[" "], "title_narrative_lang":[" "], "description.type":["1","2"], "description_type":["1","2"], "description.narrative":["The NIHR's second Global Health Research call for Units. UK universities and research institutes were invited to submit applications, working in equitable partnerships with researchers in low- and middle-income countries (LMIC), to develop their ambitions to deliver world-class applied global health research to address under-funded or under-researched global health areas specific to those countries.\nGlobal Health Research Units are defined as a well-established research partnership or network of universities and research institutes in LMICs and the UK:\n1. With an existing track-record of delivering internationally recognised applied global health research addressing unmet health needs in ODA-eligible countries;\n2. Who wish to consolidate and expand this work, supporting and developing thematic research and capacity strengthening networks, through regional and global hubs;\n3. Who will deliver a large scale, ambitious programme of applied health research through a range of trials and studies;\n4. Who are able to leverage the strength of the existing partnership consortium to improve practice and inform policy based on scientific evidence;\n5. Who will set up and deliver a substantial and sustainable programme of capacity and capability strengthening at individual and institutional level.","The strategic aim across the Global Health Research Units programme is to:\n1. Address locally-identified challenges in LMICs through equitable research partnerships between researchers and institutions in the UK and ODA-eligible countries\n2. To generate the scientific evidence that can improve health outcomes for people in low resource setting through improving practice and informing policy.\n3. Strengthen research and research management capacity and capability to support future sustainability of research in partner countries."], "description_narrative":["The NIHR's second Global Health Research call for Units. UK universities and research institutes were invited to submit applications, working in equitable partnerships with researchers in low- and middle-income countries (LMIC), to develop their ambitions to deliver world-class applied global health research to address under-funded or under-researched global health areas specific to those countries.\nGlobal Health Research Units are defined as a well-established research partnership or network of universities and research institutes in LMICs and the UK:\n1. With an existing track-record of delivering internationally recognised applied global health research addressing unmet health needs in ODA-eligible countries;\n2. Who wish to consolidate and expand this work, supporting and developing thematic research and capacity strengthening networks, through regional and global hubs;\n3. Who will deliver a large scale, ambitious programme of applied health research through a range of trials and studies;\n4. Who are able to leverage the strength of the existing partnership consortium to improve practice and inform policy based on scientific evidence;\n5. Who will set up and deliver a substantial and sustainable programme of capacity and capability strengthening at individual and institutional level.","The strategic aim across the Global Health Research Units programme is to:\n1. Address locally-identified challenges in LMICs through equitable research partnerships between researchers and institutions in the UK and ODA-eligible countries\n2. To generate the scientific evidence that can improve health outcomes for people in low resource setting through improving practice and informing policy.\n3. Strengthen research and research management capacity and capability to support future sustainability of research in partner countries."], "description_narrative_text":["The NIHR's second Global Health Research call for Units. UK universities and research institutes were invited to submit applications, working in equitable partnerships with researchers in low- and middle-income countries (LMIC), to develop their ambitions to deliver world-class applied global health research to address under-funded or under-researched global health areas specific to those countries.\nGlobal Health Research Units are defined as a well-established research partnership or network of universities and research institutes in LMICs and the UK:\n1. With an existing track-record of delivering internationally recognised applied global health research addressing unmet health needs in ODA-eligible countries;\n2. Who wish to consolidate and expand this work, supporting and developing thematic research and capacity strengthening networks, through regional and global hubs;\n3. Who will deliver a large scale, ambitious programme of applied health research through a range of trials and studies;\n4. Who are able to leverage the strength of the existing partnership consortium to improve practice and inform policy based on scientific evidence;\n5. Who will set up and deliver a substantial and sustainable programme of capacity and capability strengthening at individual and institutional level.","The strategic aim across the Global Health Research Units programme is to:\n1. Address locally-identified challenges in LMICs through equitable research partnerships between researchers and institutions in the UK and ODA-eligible countries\n2. To generate the scientific evidence that can improve health outcomes for people in low resource setting through improving practice and informing policy.\n3. Strengthen research and research management capacity and capability to support future sustainability of research in partner countries."], "description.narrative.lang":[" "," "], "description_narrative_lang":[" "," "], "participating-org.ref":["GB-GOV-10","GB-GOV-10","GB-GOV-10","GB-COH-RC000672","GB-CHC-222655","GB-UKPRN-10007790","GB-COH-04465125","GB-COH-RC000679","GB-UKPRN-10007774","GB-EDU-133784","GB-COH-RC000660","GB-COH-RC000797","GB-SC-SC004401"], "participating_org_ref":["GB-GOV-10","GB-GOV-10","GB-GOV-10","GB-COH-RC000672","GB-CHC-222655","GB-UKPRN-10007790","GB-COH-04465125","GB-COH-RC000679","GB-UKPRN-10007774","GB-EDU-133784","GB-COH-RC000660","GB-COH-RC000797","GB-SC-SC004401"], "participating-org.role":["1","2","3","4","4","4","4","4","4","4","4","4","4"], "participating_org_role":["1","2","3","4","4","4","4","4","4","4","4","4","4"], "participating-org.type":["10","10","10","80","80","80","80","80","80","80","80","80","80"], "participating_org_type":["10","10","10","80","80","80","80","80","80","80","80","80","80"], "participating-org.narrative":["UK - Department of Health and Social Care (DHSC)","UK - Department of Health and Social Care (DHSC)","UK - Department of Health and Social Care (DHSC)","University of Sussex","Liverpool School of Tropical Medicine","The University of Edinburgh","Imperial College London","University of York","University of Oxford","University of Birmingham","University of Liverpool","The University of Manchester","University of Glasgow"], "participating_org_narrative":["UK - Department of Health and Social Care (DHSC)","UK - Department of Health and Social Care (DHSC)","UK - Department of Health and Social Care (DHSC)","University of Sussex","Liverpool School of Tropical Medicine","The University of Edinburgh","Imperial College London","University of York","University of Oxford","University of Birmingham","University of Liverpool","The University of Manchester","University of Glasgow"], "participating_org_narrative_text":["UK - Department of Health and Social Care (DHSC)","UK - Department of Health and Social Care (DHSC)","UK - Department of Health and Social Care (DHSC)","University of Sussex","Liverpool School of Tropical Medicine","The University of Edinburgh","Imperial College London","University of York","University of Oxford","University of Birmingham","University of Liverpool","The University of Manchester","University of Glasgow"], "participating-org.narrative.lang":[" "," "," "," "," "," "," "," "," "," "," "," "," "], "participating_org_narrative_lang":[" "," "," "," "," "," "," "," "," "," "," "," "," "], "activity-status.code":"2", "activity_status_code":"2", "activity-date.iso-date":["2021-07-01T00:00:00Z","2021-07-01T00:00:00Z","2027-08-31T00:00:00Z"], "activity_date_iso_date":["2021-07-01T00:00:00Z","2021-07-01T00:00:00Z","2027-08-31T00:00:00Z"], "activity-date.type":["1","2","3"], "activity_date_type":["1","2","3"], "contact-info.type":["1"], "contact_info_type":["1"], "contact-info.organisation.narrative":["UK - Department of Health and Social Care (DHSC)"], "contact_info_organisation_narrative":["UK - Department of Health and Social Care (DHSC)"], "contact_info_organisation_narrative_text":["UK - Department of Health and Social Care (DHSC)"], "contact-info.organisation.narrative.lang":[" "], "contact_info_organisation_narrative_lang":[" "], "contact-info.department.narrative":["Science, Research and Evidence"], "contact_info_department_narrative":["Science, Research and Evidence"], "contact_info_department_narrative_text":["Science, Research and Evidence"], "contact-info.department.narrative.lang":[" "], "contact_info_department_narrative_lang":[" "], "contact-info.person-name.narrative":["Global Health Research Programme"], "contact_info_person_name_narrative":["Global Health Research Programme"], "contact_info_person_name_narrative_text":["Global Health Research Programme"], "contact-info.person-name.narrative.lang":[" "], "contact_info_person_name_narrative_lang":[" "], "contact-info.email":["GlobalHealthResearch@dhsc.gov.uk"], "contact_info_email":["GlobalHealthResearch@dhsc.gov.uk"], "contact-info.website":["https://www.nihr.ac.uk/funding-and-support/global-health-research/"], "contact_info_website":["https://www.nihr.ac.uk/funding-and-support/global-health-research/"], "contact-info.mailing-address.narrative":["7th Floor South Wing, 39 Victoria Street, London, SW1H 0EU"], "contact_info_mailing_address_narrative":["7th Floor South Wing, 39 Victoria Street, London, SW1H 0EU"], "contact_info_mailing_address_narrative_text":["7th Floor South Wing, 39 Victoria Street, London, SW1H 0EU"], "contact-info.mailing-address.narrative.lang":[" "], "contact_info_mailing_address_narrative_lang":[" "], "activity-scope.code":"1", "activity_scope_code":"1", "recipient-region.code":["998"], "recipient_region_code":["998"], "recipient-region.vocabulary":["1"], "recipient_region_vocabulary":["1"], "sector.code":["12182"], "sector_code":["12182"], "sector.percentage":[100.0], "sector_percentage":[100.0], "sector.vocabulary":["1"], "sector_vocabulary":["1"], "sector.narrative":["Medical research"], "sector_narrative":["Medical research"], "sector_narrative_text":["Medical research"], "sector.narrative.lang":[" "], "sector_narrative_lang":[" "], "tag.code":["RI"], "tag_code":["RI"], "tag.vocabulary":["99"], "tag_vocabulary":["99"], "tag.vocabulary-uri":["https://devtracker.fcdo.gov.uk/custom-codes"], "tag_vocabulary_uri":["https://devtracker.fcdo.gov.uk/custom-codes"], "tag.narrative":["Research and Innovation"], "tag_narrative":["Research and Innovation"], "tag_narrative_text":["Research and Innovation"], "tag.narrative.lang":[" "], "tag_narrative_lang":[" "], "collaboration-type.code":"1", "collaboration_type_code":"1", "default-flow-type.code":"10", "default_flow_type_code":"10", "default-finance-type.code":"110", "default_finance_type_code":"110", "default-aid-type.code":["D02"], "default_aid_type":["D02"], "default_aid_type_category_code":["D02"], "default_aid_type_code":["D02"], "default-tied-status.code":"5", "default_tied_status_code":"5", "capital-spend.percentage":100.0, "capital_spend_percentage":100.0, "document-link.format":["application/pdf","application/pdf","text/html","application/pdf","application/pdf"], "document_link_format":["application/pdf","application/pdf","text/html","application/pdf","application/pdf"], "document-link.url":["https://drive.google.com/file/d/16BvRhBbJkSnlJiX6lpbHe-odFLxhrZIv/view?usp=drive_link","https://www.nihr.ac.uk/documents/second-call-for-global-health-research-units-remit-and-guidance/24947","https://www.nihr.ac.uk/documents/global-health-research-units-and-groups-theory-of-change/26037","https://drive.google.com/open?id=17luarPhNy0X0s_Pk22uKB4RUAURqNfXF&usp=drive_copy","https://drive.google.com/open?id=128OUuKTbeG9B-I6uTn9uqPy2mFsLarMg&usp=drive_copy"], "document_link_url":["https://drive.google.com/file/d/16BvRhBbJkSnlJiX6lpbHe-odFLxhrZIv/view?usp=drive_link","https://www.nihr.ac.uk/documents/second-call-for-global-health-research-units-remit-and-guidance/24947","https://www.nihr.ac.uk/documents/global-health-research-units-and-groups-theory-of-change/26037","https://drive.google.com/open?id=17luarPhNy0X0s_Pk22uKB4RUAURqNfXF&usp=drive_copy","https://drive.google.com/open?id=128OUuKTbeG9B-I6uTn9uqPy2mFsLarMg&usp=drive_copy"], "document-link.title.narrative":["Call 2 Units 2024 Annual Review ","Call Specification Units Call 2","Theory of Change Units","Units Annual Review 2022","Units Call 2 Annual Review 2023 "], "document_link_title_narrative":["Call 2 Units 2024 Annual Review ","Call Specification Units Call 2","Theory of Change Units","Units Annual Review 2022","Units Call 2 Annual Review 2023 "], "document_link_title_narrative_text":["Call 2 Units 2024 Annual Review ","Call Specification Units Call 2","Theory of Change Units","Units Annual Review 2022","Units Call 2 Annual Review 2023 "], "document-link.title.narrative.lang":[" "," "," "," "," "], "document_link_title_narrative_lang":[" "," "," "," "," "], "document-link.category.code":["A07","A08","A02","A12","A10","A02","A12","A07","A08","A07","A08"], "document_link_category_code":["A07","A08","A02","A12","A10","A02","A12","A07","A08","A07","A08"], "document-link.language.code":["en","en","en","en","en"], "document_link_language_code":["en","en","en","en","en"], "document-link.document-date.iso-date":["2025-06-19T00:00:00Z","2020-05-28T00:00:00Z","2020-11-04T00:00:00Z","2024-01-17T00:00:00Z","2024-08-27T00:00:00Z"], "document_link_document_date_iso_date":["2025-06-19T00:00:00Z","2020-05-28T00:00:00Z","2020-11-04T00:00:00Z","2024-01-17T00:00:00Z","2024-08-27T00:00:00Z"], "related-activity.ref":["GB-GOV-10-GHRU_2_131996","GB-GOV-10-GHRU_2_132027","GB-GOV-10-GHRU_2_132826","GB-GOV-10-GHRU_2_132960","GB-GOV-10-GHRU_2_133252","GB-GOV-10-GHRU_2_133307","GB-GOV-10-GHRU_2_133364","GB-GOV-10-GHRU_2_134530","GB-GOV-10-GHRU_2_134702","GB-GOV-10-GHRU_2_134801"], "related_activity_ref":["GB-GOV-10-GHRU_2_131996","GB-GOV-10-GHRU_2_132027","GB-GOV-10-GHRU_2_132826","GB-GOV-10-GHRU_2_132960","GB-GOV-10-GHRU_2_133252","GB-GOV-10-GHRU_2_133307","GB-GOV-10-GHRU_2_133364","GB-GOV-10-GHRU_2_134530","GB-GOV-10-GHRU_2_134702","GB-GOV-10-GHRU_2_134801"], "related-activity.type":["2","2","2","2","2","2","2","2","2","2"], "related_activity_type":["2","2","2","2","2","2","2","2","2","2"], "conditions.attached":false, "conditions_attached":"0", "reporting-org.type.name":"Government", "reporting_org_type_name":"Government", "recipient-region.name":["Developing countries, unspecified"], "recipient_region_name":["Developing countries, unspecified"], "default-aid-type.name":["Other technical assistance"], "default_aid_type_category_name":["Other technical assistance"], "tag.vocabulary.name":["Reporting Organisation"], "title.narrative.first":"NIHR Global Health Research Units: Call 2", "title_narrative_first":"NIHR Global Health Research Units: Call 2", "activity-date.start-planned":"2021-07-01T00:00:00Z", "activity_date_start_planned":"Thu Jul 01 00:00:00 UTC 2021", "activity_date_start_planned_f":"2021-07-01T00:00:00Z", "activity-date.common.start":"2021-07-01T00:00:00Z", "activity_date_start_common":"Thu Jul 01 00:00:00 UTC 2021", "activity_date_start_common_f":"2021-07-01T00:00:00Z", "activity-date.start-actual":"2021-07-01T00:00:00Z", "activity_date_start_actual":"Thu Jul 01 00:00:00 UTC 2021", "activity_date_start_actual_f":"2021-07-01T00:00:00Z", "activity-date.end-planned":"2027-08-31T00:00:00Z", "activity_date_end_planned":"Tue Aug 31 00:00:00 UTC 2027", "activity_date_end_planned_f":"2027-08-31T00:00:00Z", "activity-date.common.end":"2027-08-31T00:00:00Z", "activity_date_end_common":"Tue Aug 31 00:00:00 UTC 2027", "activity_date_end_common_f":"2027-08-31T00:00:00Z", "activity-status.text":"Implementation", "activity_status_text":"Implementation", "dataset.id":"bce0347a-c08e-4d93-86ce-c44d7adc5c93", "dataset_iati_id":"bce0347a-c08e-4d93-86ce-c44d7adc5c93", "dataset.name":"dhsc-activities-ghr", "dataset_name":"dhsc-activities-ghr", "dataset.extras.iati_version":"2.03", "dataset.resources.hash":"5a2fa4a2f378e3034bb8e88e541b337f92b20e0f", "dataset.resources.url":"https://dhsc-govuk.github.io/iati-oda-spending-metadata/dhsc-activities-ghr.xml", "activity-date.quarter":[3,3,3], "document-link.document-date.quarter":[2,2,4,1,3], "document-link.category-codes-combined":["A07,A08,A02","A12,A10","A02,A12","A07,A08","A07,A08"], "child-aggregation.budget.value":7.01892019E7, "child_aggregation_budget_value":7.01892019E7, "activity-plus-child-aggregation.budget.value":7.01892019E7, "activity_plus_child_aggregation_budget_value":7.01892019E7, "child-aggregation.budget.currency":"USD", "child_aggregation_budget_currency":"USD", "activity-plus-child-aggregation.budget.currency":"USD", "activity_plus_child_aggregation_budget_currency":"USD", "child-aggregation.budget.value-usd":8.904799917656347E7, "child_aggregation_budget_value_usd":8.904799917656347E7, "activity-plus-child-aggregation.budget.value-usd":8.904799917656347E7, "activity_plus_child_aggregation_budget_value_usd":8.904799917656347E7, "child-aggregation.budget.value-gbp":7.01892019E7, "child_aggregation_budget_value_gbp":7.01892019E7, "activity-plus-child-aggregation.budget.value-gbp":7.01892019E7, "activity_plus_child_aggregation_budget_value_gbp":7.01892019E7, "child-aggregation.outgoing-commitment.value":7.01892019E7, "child_aggregation_commitment_value":7.01892019E7, "activity-plus-child-aggregation.outgoing-commitment.value":7.01892019E7, "activity_plus_child_aggregation_commitment_value":7.01892019E7, "child-aggregation.outgoing-commitment.currency":"USD", "child_aggregation_commitment_currency":"USD", "activity-plus-child-aggregation.outgoing-commitment.currency":"USD", "activity_plus_child_aggregation_commitment_currency":"USD", "child-aggregation.outgoing-commitment.value-usd":8.903807763990992E7, "child_aggregation_commitment_value_usd":8.903807763990992E7, "activity-plus-child-aggregation.outgoing-commitment.value-usd":8.903807763990992E7, "activity_plus_child_aggregation_commitment_value_usd":8.903807763990992E7, "child-aggregation.outgoing-commitment.value-gbp":7.01892019E7, "child_aggregation_commitment_value_gbp":7.01892019E7, "activity-plus-child-aggregation.outgoing-commitment.value-gbp":7.01892019E7, "activity_plus_child_aggregation_commitment_value_gbp":7.01892019E7, "child-aggregation.disbursement.value":4.902156311E7, "child_aggregation_disbursement_value":4.902156311E7, "activity-plus-child-aggregation.disbursement.value":4.902156311E7, "activity_plus_child_aggregation_disbursement_value":4.902156311E7, "child-aggregation.disbursement.currency":"USD", "child_aggregation_disbursement_currency":"USD", "activity-plus-child-aggregation.disbursement.currency":"USD", "activity_plus_child_aggregation_disbursement_currency":"USD", "child-aggregation.disbursement.value-usd":6.2213576896277755E7, "child_aggregation_disbursement_value_usd":6.2213576896277755E7, "activity-plus-child-aggregation.disbursement.value-usd":6.2213576896277755E7, "activity_plus_child_aggregation_disbursement_value_usd":6.2213576896277755E7, "child-aggregation.disbursement.value-gbp":4.902156311E7, "child_aggregation_disbursement_value_gbp":4.902156311E7, "activity-plus-child-aggregation.disbursement.value-gbp":4.902156311E7, "activity_plus_child_aggregation_disbursement_value_gbp":4.902156311E7, "json.reporting-org":"{\"ref\": \"GB-GOV-10\", \"type\": 10, \"narrative\": \"UK - Department of Health and Social Care (DHSC)\", \"narrative.lang\": \" \"}", "json.title":"{\"narrative\": \"NIHR Global Health Research Units: Call 2\", \"narrative.lang\": \" \"}", "json.description":["{\"type\": 1, \"narrative\": \"The NIHR's second Global Health Research call for Units. UK universities and research institutes were invited to submit applications, working in equitable partnerships with researchers in low- and middle-income countries (LMIC), to develop their ambitions to deliver world-class applied global health research to address under-funded or under-researched global health areas specific to those countries.\\nGlobal Health Research Units are defined as a well-established research partnership or network of universities and research institutes in LMICs and the UK:\\n1. With an existing track-record of delivering internationally recognised applied global health research addressing unmet health needs in ODA-eligible countries;\\n2. Who wish to consolidate and expand this work, supporting and developing thematic research and capacity strengthening networks, through regional and global hubs;\\n3. Who will deliver a large scale, ambitious programme of applied health research through a range of trials and studies;\\n4. Who are able to leverage the strength of the existing partnership consortium to improve practice and inform policy based on scientific evidence;\\n5. Who will set up and deliver a substantial and sustainable programme of capacity and capability strengthening at individual and institutional level.\", \"narrative.lang\": \" \"}","{\"type\": 2, \"narrative\": \"The strategic aim across the Global Health Research Units programme is to:\\n1. Address locally-identified challenges in LMICs through equitable research partnerships between researchers and institutions in the UK and ODA-eligible countries\\n2. To generate the scientific evidence that can improve health outcomes for people in low resource setting through improving practice and informing policy.\\n3. Strengthen research and research management capacity and capability to support future sustainability of research in partner countries.\", \"narrative.lang\": \" \"}"], "json.participating-org":["{\"ref\": \"GB-GOV-10\", \"role\": 1, \"type\": 10, \"narrative\": \"UK - Department of Health and Social Care (DHSC)\", \"narrative.lang\": \" \"}","{\"ref\": \"GB-GOV-10\", \"role\": 2, \"type\": 10, \"narrative\": \"UK - Department of Health and Social Care (DHSC)\", \"narrative.lang\": \" \"}","{\"ref\": \"GB-GOV-10\", \"role\": 3, \"type\": 10, \"narrative\": \"UK - Department of Health and Social Care (DHSC)\", \"narrative.lang\": \" \"}","{\"ref\": \"GB-COH-RC000672\", \"role\": 4, \"type\": 80, \"narrative\": \"University of Sussex\", \"narrative.lang\": \" \"}","{\"ref\": \"GB-CHC-222655\", \"role\": 4, \"type\": 80, \"narrative\": \"Liverpool School of Tropical Medicine\", \"narrative.lang\": \" \"}","{\"ref\": \"GB-UKPRN-10007790\", \"role\": 4, \"type\": 80, \"narrative\": \"The University of Edinburgh\", \"narrative.lang\": \" \"}","{\"ref\": \"GB-COH-04465125\", \"role\": 4, \"type\": 80, \"narrative\": \"Imperial College London\", \"narrative.lang\": \" \"}","{\"ref\": \"GB-COH-RC000679\", \"role\": 4, \"type\": 80, \"narrative\": \"University of York\", \"narrative.lang\": \" \"}","{\"ref\": \"GB-UKPRN-10007774\", \"role\": 4, \"type\": 80, \"narrative\": \"University of Oxford\", \"narrative.lang\": \" \"}","{\"ref\": \"GB-EDU-133784\", \"role\": 4, \"type\": 80, \"narrative\": \"University of Birmingham\", \"narrative.lang\": \" \"}","{\"ref\": \"GB-COH-RC000660\", \"role\": 4, \"type\": 80, \"narrative\": \"University of Liverpool\", \"narrative.lang\": \" \"}","{\"ref\": \"GB-COH-RC000797\", \"role\": 4, \"type\": 80, \"narrative\": \"The University of Manchester\", \"narrative.lang\": \" \"}","{\"ref\": \"GB-SC-SC004401\", \"role\": 4, \"type\": 80, \"narrative\": \"University of Glasgow\", \"narrative.lang\": \" \"}"], "json.activity-date":["{\"iso-date\": \"2021-07-01\", \"type\": 1}","{\"iso-date\": \"2021-07-01\", \"type\": 2}","{\"iso-date\": \"2027-08-31\", \"type\": 3}"], "json.contact-info":["{\"type\": 1, \"organisation\": {\"narrative\": \"UK - Department of Health and Social Care (DHSC)\", \"narrative.lang\": \" \"}, \"department\": {\"narrative\": \"Science, Research and Evidence\", \"narrative.lang\": \" \"}, \"person-name\": {\"narrative\": \"Global Health Research Programme\", \"narrative.lang\": \" \"}, \"email\": \"GlobalHealthResearch@dhsc.gov.uk\", \"website\": \"https://www.nihr.ac.uk/funding-and-support/global-health-research/\", \"mailing-address\": {\"narrative\": \"7th Floor South Wing, 39 Victoria Street, London, SW1H 0EU\", \"narrative.lang\": \" \"}}"], "json.recipient-region":["{\"code\": 998, \"vocabulary\": 1}"], "json.sector":["{\"code\": 12182, \"percentage\": 100, \"vocabulary\": 1, \"narrative\": \"Medical research\", \"narrative.lang\": \" \"}"], "json.tag":["{\"code\": \"RI\", \"vocabulary\": 99, \"vocabulary-uri\": \"https://devtracker.fcdo.gov.uk/custom-codes\", \"narrative\": \"Research and Innovation\", \"narrative.lang\": \" \"}"], "json.default-aid-type":["{\"code\": \"D02\"}"], "json.document-link":["{\"format\": \"application/pdf\", \"url\": \"https://drive.google.com/file/d/16BvRhBbJkSnlJiX6lpbHe-odFLxhrZIv/view?usp=drive_link\", \"title\": {\"narrative\": \"Call 2 Units 2024 Annual Review \", \"narrative.lang\": \" \"}, \"category\": [{\"code\": \"A07\"}, {\"code\": \"A08\"}, {\"code\": \"A02\"}], \"language\": {\"code\": \"en\"}, \"document-date\": [{\"iso-date\": \"2025-06-19\"}]}","{\"format\": \"application/pdf\", \"url\": \"https://www.nihr.ac.uk/documents/second-call-for-global-health-research-units-remit-and-guidance/24947\", \"title\": {\"narrative\": \"Call Specification Units Call 2\", \"narrative.lang\": \" \"}, \"category\": [{\"code\": \"A12\"}, {\"code\": \"A10\"}], \"language\": {\"code\": \"en\"}, \"document-date\": [{\"iso-date\": \"2020-05-28\"}]}","{\"format\": \"text/html\", \"url\": \"https://www.nihr.ac.uk/documents/global-health-research-units-and-groups-theory-of-change/26037\", \"title\": {\"narrative\": \"Theory of Change Units\", \"narrative.lang\": \" \"}, \"category\": [{\"code\": \"A02\"}, {\"code\": \"A12\"}], \"language\": {\"code\": \"en\"}, \"document-date\": [{\"iso-date\": \"2020-11-04\"}]}","{\"format\": \"application/pdf\", \"url\": \"https://drive.google.com/open?id=17luarPhNy0X0s_Pk22uKB4RUAURqNfXF&usp=drive_copy\", \"title\": {\"narrative\": \"Units Annual Review 2022\", \"narrative.lang\": \" \"}, \"category\": [{\"code\": \"A07\"}, {\"code\": \"A08\"}], \"language\": {\"code\": \"en\"}, \"document-date\": [{\"iso-date\": \"2024-01-17\"}]}","{\"format\": \"application/pdf\", \"url\": \"https://drive.google.com/open?id=128OUuKTbeG9B-I6uTn9uqPy2mFsLarMg&usp=drive_copy\", \"title\": {\"narrative\": \"Units Call 2 Annual Review 2023 \", \"narrative.lang\": \" \"}, \"category\": [{\"code\": \"A07\"}, {\"code\": \"A08\"}], \"language\": {\"code\": \"en\"}, \"document-date\": [{\"iso-date\": \"2024-08-27\"}]}"], "json.related-activity":["{\"ref\": \"GB-GOV-10-GHRU_2_131996\", \"type\": 2}","{\"ref\": \"GB-GOV-10-GHRU_2_132027\", \"type\": 2}","{\"ref\": \"GB-GOV-10-GHRU_2_132826\", \"type\": 2}","{\"ref\": \"GB-GOV-10-GHRU_2_132960\", \"type\": 2}","{\"ref\": \"GB-GOV-10-GHRU_2_133252\", \"type\": 2}","{\"ref\": \"GB-GOV-10-GHRU_2_133307\", \"type\": 2}","{\"ref\": \"GB-GOV-10-GHRU_2_133364\", \"type\": 2}","{\"ref\": \"GB-GOV-10-GHRU_2_134530\", \"type\": 2}","{\"ref\": \"GB-GOV-10-GHRU_2_134702\", \"type\": 2}","{\"ref\": \"GB-GOV-10-GHRU_2_134801\", \"type\": 2}"], "json.conditions":"{\"attached\": 0}", "related_budget_value":[670986,1310320,1407376,1458040,1265920,887017,893649,1297456,1490644,1819762,1122679,644191,1210840,2232864,1777640,1321048,456963,719658,1177484,1876040,1757644,790008,679166,886149,1370944,1242248,1274280,1314168,898467,881149,1370944,1242248,1274280,1314168,898467,872770,1699224,1602936,1324176,920716,580178,1331722,1479372,1448284,1222092,1078880,438944,1237467,1429804,1405252,1376584,1071192,434725,1288463,1509956,1375680,1253696,1128972,443208], "related_budget_period_start_quarter":[2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2], "related_budget_period_end_quarter":[1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1], "related_budget_period_start_iso_date":["2021-04-01T00:00:00Z","2022-04-01T00:00:00Z","2023-04-01T00:00:00Z","2024-04-01T00:00:00Z","2025-04-01T00:00:00Z","2026-04-01T00:00:00Z","2021-04-01T00:00:00Z","2022-04-01T00:00:00Z","2023-04-01T00:00:00Z","2024-04-01T00:00:00Z","2025-04-01T00:00:00Z","2026-04-01T00:00:00Z","2022-04-01T00:00:00Z","2023-04-01T00:00:00Z","2024-04-01T00:00:00Z","2025-04-01T00:00:00Z","2026-04-01T00:00:00Z","2021-04-01T00:00:00Z","2022-04-01T00:00:00Z","2023-04-01T00:00:00Z","2024-04-01T00:00:00Z","2025-04-01T00:00:00Z","2026-04-01T00:00:00Z","2022-04-01T00:00:00Z","2023-04-01T00:00:00Z","2024-04-01T00:00:00Z","2025-04-01T00:00:00Z","2026-04-01T00:00:00Z","2027-04-01T00:00:00Z","2022-04-01T00:00:00Z","2023-04-01T00:00:00Z","2024-04-01T00:00:00Z","2025-04-01T00:00:00Z","2026-04-01T00:00:00Z","2027-04-01T00:00:00Z","2021-04-01T00:00:00Z","2022-04-01T00:00:00Z","2023-04-01T00:00:00Z","2024-04-01T00:00:00Z","2025-04-01T00:00:00Z","2026-04-01T00:00:00Z","2022-04-01T00:00:00Z","2023-04-01T00:00:00Z","2024-04-01T00:00:00Z","2025-04-01T00:00:00Z","2026-04-01T00:00:00Z","2027-04-01T00:00:00Z","2022-04-01T00:00:00Z","2023-04-01T00:00:00Z","2024-04-01T00:00:00Z","2025-04-01T00:00:00Z","2026-04-01T00:00:00Z","2027-04-01T00:00:00Z","2022-04-01T00:00:00Z","2023-04-01T00:00:00Z","2024-04-01T00:00:00Z","2025-04-01T00:00:00Z","2026-04-01T00:00:00Z","2027-04-01T00:00:00Z"], "related_budget_period_end_iso_date":["2022-03-31T00:00:00Z","2023-03-31T00:00:00Z","2024-03-31T00:00:00Z","2025-03-31T00:00:00Z","2026-03-31T00:00:00Z","2027-03-31T00:00:00Z","2022-03-31T00:00:00Z","2023-03-31T00:00:00Z","2024-03-31T00:00:00Z","2025-03-31T00:00:00Z","2026-03-31T00:00:00Z","2027-03-31T00:00:00Z","2023-03-31T00:00:00Z","2024-03-31T00:00:00Z","2025-03-31T00:00:00Z","2026-03-31T00:00:00Z","2027-03-31T00:00:00Z","2022-03-31T00:00:00Z","2023-03-31T00:00:00Z","2024-03-31T00:00:00Z","2025-03-31T00:00:00Z","2026-03-31T00:00:00Z","2027-03-31T00:00:00Z","2023-03-31T00:00:00Z","2024-03-31T00:00:00Z","2025-03-31T00:00:00Z","2026-03-31T00:00:00Z","2027-03-31T00:00:00Z","2028-03-31T00:00:00Z","2023-03-31T00:00:00Z","2024-03-31T00:00:00Z","2025-03-31T00:00:00Z","2026-03-31T00:00:00Z","2027-03-31T00:00:00Z","2028-03-31T00:00:00Z","2022-03-31T00:00:00Z","2023-03-31T00:00:00Z","2024-03-31T00:00:00Z","2025-03-31T00:00:00Z","2026-03-31T00:00:00Z","2027-03-31T00:00:00Z","2023-03-31T00:00:00Z","2024-03-31T00:00:00Z","2025-03-31T00:00:00Z","2026-03-31T00:00:00Z","2027-03-31T00:00:00Z","2028-03-31T00:00:00Z","2023-03-31T00:00:00Z","2024-03-31T00:00:00Z","2025-03-31T00:00:00Z","2026-03-31T00:00:00Z","2027-03-31T00:00:00Z","2028-03-31T00:00:00Z","2023-03-31T00:00:00Z","2024-03-31T00:00:00Z","2025-03-31T00:00:00Z","2026-03-31T00:00:00Z","2027-03-31T00:00:00Z","2028-03-31T00:00:00Z"], "id":"4bd3d225-0c90-4f08-822e-50b47a0f2ffa", "related_activity_context":"ID: GB-GOV-10-NIHR_GHRU2\nTitle: NIHR Global Health Research Units: Call 2\nDescription: The NIHR's second Global Health Research call for Units. UK universities and research institutes were invited to submit applications, working in equitable partnerships with researchers in low- and middle-income countries (LMIC), to develop their ambitions to deliver world-class applied global health research to address under-funded or under-researched global health areas specific to those countries.\nGlobal Health Research Units are defined as a well-established research partnership or network of universities and research institutes in LMICs and the UK:\n1. With an existing track-record of delivering internationally recognised applied global health research addressing unmet health needs in ODA-eligible countries;\n2. Who wish to consolidate and expand this work, supporting and developing thematic research and capacity strengthening networks, through regional and global hubs;\n3. Who will deliver a large scale, ambitious programme of applied health research through a range of trials and studies;\n4. Who are able to leverage the strength of the existing partnership consortium to improve practice and inform policy based on scientific evidence;\n5. Who will set up and deliver a substantial and sustainable programme of capacity and capability strengthening at individual and institutional level.. The strategic aim across the Global Health Research Units programme is to:\n1. Address locally-identified challenges in LMICs through equitable research partnerships between researchers and institutions in the UK and ODA-eligible countries\n2. To generate the scientific evidence that can improve health outcomes for people in low resource setting through improving practice and informing policy.\n3. Strengthen research and research management capacity and capability to support future sustainability of research in partner countries.\n \n ID: GB-GOV-10-GHRU_2_131996\nTitle: NIHR Global Health Research Unit on Neglected Tropical Diseases at Brighton and Sussex Medical School (Phase 2)\nDescription: Since 2017, the NIHR Global Health Research Unit (GHRU) on Neglected Tropical Diseases (NTDs) at Brighton and Sussex Medical School has carried out a highly successful needs-driven research programme in partnership with Addis Ababa University and the Armauer Hansen Research Institute in Ethiopia, and the Mycetoma Research Centre, University of Khartoum, Sudan. \n\nOur GHRU has focused on three conditions considered severely neglected in terms of research, public attention and political will: \n1.\tpodoconiosis (a progressive, disabling form of leg swelling seen in barefoot farmers)\n2.\tmycetoma (a destructive infection of the skin and underlying tissues) \n3.\tscabies (a profoundly irritating skin condition caused by burrowing mites)\n\nOur studies have spanned wide-ranging disciplines to address questions directly relevant to national and global NTD elimination agendas. \n\nThis research has been conducted within a strong framework of capacity strengthening which has developed infrastructure and financial management at partner institutions and trained 11 PhD students and five post-doctoral researchers. All early career researchers have benefitted from training opportunities within and beyond their countries, and from the NIHR Global Health Academy. We will build on these strong foundations in the next five years and expand the partnership to include the University of Rwanda.\n\nWe will use a range of methods to investigate new research questions clustered into four interrelated themes: \n1.\tmechanisms of disease\n2.\tgeospatial mapping\n3.\tdiagnostics and drug development\n4.\timplementation research\n\nThe questions have been prioritised through a process of: \n1.\tidentifying the areas in which our GHRU has had the most impact\n2.\tparticipating in WHO and disease-group identification of research gaps in these areas\n3.\tconsulting with stakeholders including patients, communities, implementers and policy makers. \n\nOur research will contribute evidence important to disease treatment and prevention strategies and continue to enhance research capacity to ensure sustainability.. Scientific Objectives: \n1.\tinvestigate pathogen genetic diversity and/or host susceptibility to each condition\n2.\timprove understanding of the disease burden and distribution of each condition through a combination of field-based mapping and geo-spatial modelling\n3.\tidentify new diagnostics and treatments for scabies\n4.\tevaluate services to improve prevention, diagnosis and care of these conditions, in particular integrating these with other skin-NTDs\n\nStrategic Objectives:\n1.\tdevelop a network of researchers studying podoconiosis, mycetoma and scabies across three DAC countries\n2.\tincrease societal awareness and expand the evidence base for national and international policy relating to these three NTDs\n\nCapacity Strengthening Objectives:\n\n1.\tsupport endemic-country PhD and postdoctoral training posts so that capacity for research into NTDs is expanded\n2.\tstrengthen the research environment in which our collaborators and trainees work\n \n ID: GB-GOV-10-GHRU_2_132027\nTitle: NIHR Global Health Research Unit on Stillbirth and Neonatal Death\nDescription: The NIHR Global Health Unit on the Prevention and Management of Stillbirths and Neonatal Deaths in Sub-Saharan Africa and South Asia, led from the Centre for Childbirth, Women’s and Newborn Health at Liverpool School of Tropical Medicine UK, is an established equitable multidisciplinary partnership between Africa, Asia and UK-based researchers. As an international centre of research excellence, our goal is to end preventable stillbirths and newborn deaths, ensure adequate support for parents and families whose baby dies and reduce associated stigma. \n\nUsing a whole systems approach, we work across high burden settings in India, Kenya, Malawi, Pakistan, Tanzania, Uganda, Zambia and Zimbabwe. We aim to develop, test and implement sustainable and cost-effective solutions to strengthen maternity and newborn care, reducing mortality and morbidity through high-quality, respectful and compassionate maternity and newborn care. \n\nActivities cover the entire spectrum of maternal and newborn health from preconception to post/neonatal care, with a strong focus on meaningful community and stakeholder partnerships. We co-produce research with women, families, front-line health workers and policy makers. \n\nWorking across 10 work streams, we are drawing on the team’s methodological expertise to deliver impactful findings from evidence syntheses, exploratory studies (qualitative and quantitative approaches), core outcomes sets, clinical trials and implementation research. \n\nCapacity strengthening for maternal and newborn health research, across all partner countries is embedded throughout the Unit. We have a particular, but not exclusive, interest and experience in developing midwifery and nursing research capacity to address global shortages in these disciplines. Our development programmes spans 3 masters students, 9 PhD placements and 3 post-doctoral fellowships as well as project specific and institutional skills training.. 1.\tDevelop and evaluate sustainable, cost-effective solutions to strengthen maternity and newborn care and reduce stillbirths and neonatal deaths in high-burden settings (Kenya, Malawi, Tanzania, Uganda, Zambia, Zimbabwe, India, Pakistan). \n2.\tDetermine how best to support parents, families, attending health providers and communities who experience a stillbirth or neonatal death. \n3.\tStrengthen research capacity with particular (but not exclusive) emphasis on midwives and nurses.\n4.\tCreate and embed mechanisms of knowledge-transfer in high-burden settings.\n \n ID: GB-GOV-10-GHRU_2_132826\nTitle: NIHR Global Health Research Unit on Respiratory Health (RESPIRE-2)\nDescription: Vision: To improve quality of life and reduce the number of deaths from respiratory disorders by expanding research infrastructure, capacity and capability to conduct outstanding applied respiratory research, creating an Asian respiratory translational research network of excellence.\n\nThe aim of RESPIRE (Phase 2) is to deliver low-cost, scalable policy and clinical interventions which address locally-identified problems. We aim to act as a source of expertise and resource to policymakers, ministries of health, health workers and communities in our 7 ODA eligible partner countries across Asia (Pakistan, Sri Lanka, Bangladesh, India, Indonesia, Bhutan, Malaysia). Our Unit aims to build on the capacity development, research outputs and relationships from RESPIRE (Phase 1: 2017-2022) to contribute to improving global respiratory health. In so doing, RESPIRE aims to disseminate knowledge on existing evidence-based interventions that can be adapted for Asian settings, promote innovation to generate and evaluate new interventions and approaches, provide technical support to implementation of respiratory health programmes and identify/develop and promote innovative new approaches and delivery mechanisms. \n\nOur overarching objectives include: Building research and research management capacity in our Asian partner countries; ensuring research is driven by the needs/priorities of LMIC populations and is based on equitable/respectful partnerships; strengthening capacity to translate research findings into impact; engaging stakeholders, involving patients and communities, where appropriate, as key partners at all stages; and considering the context of COVID-19, where relevant. . Short-term (year 1):\n• Promote respectful and equitable partnerships and shared values on research governance and ethical conduct of research across RESPIRE; \n• Establish RESPIRE governance and administrative arrangements (including due diligence, research contracts and financial reporting), ensuring deliverables and reports are completed on time; \n• Set up and commence agreed programmes of work (including submitting governance (sponsorship) and ethics applications where needed) within the Unit research programmes and platforms.\n\nMedium-term (years 2-3):\n• Maintain close monitoring of and support to research programmes giving assistance in problem solving and taking risk mitigation action, where necessary; \n• Ensure translational platforms are having an impact on the work of the Unit in the areas of stakeholder engagement, education/capacity building, data science and digital health and innovation; \n• Ensure the Translational Platforms Coordination Group is working effectively to integrate Unit outputs and these are being used effectively to have an impact on respiratory health policy and practice in partner countries; \n• Ensure study findings are communicated to local communities and consultation takes place to co-develop plans for follow on actions; \n• Submit collaborative follow-on grants to extend work and tackle gaps that have been identified; \n• Develop plans for longer term sustainability.\n\nLong-term (years 3-4):\n• Ensure the Translational Platforms Coordination Group is maximising the local, regional and global impact from the new knowledge and experience generated by RESPIRE; \n• Communicate RESPIRE-2 findings to policymakers, health professionals and communities through publication in respected journals, presentation at national/regional and global meetings and publication in social media; \n• Submit collaborative follow-on grants to sustain RESPIRE activities into the future.\n \n ID: GB-GOV-10-GHRU_2_132960\nTitle: NIHR Global Health Research Unit and Network for Diabetes and Cardiovascular disease in South Asia\nDescription: Theme 1. Understanding the drivers of diabetes and cardiovascular disease in South Asia\n\nSouth Asians (SAs) are recognised to be at increased risk of both cardiovascular disease (CVD) and type 2 diabetes (T2D) compared to European populations. Data from the UK, Europe and North America suggests that the high risk of CVD and T2D in SAs is not explained by differences in traditional cardiovascular or metabolic risk factors.\n\nWe will advance understanding of the lifestyle, environmental and molecular factors influencing T2D and CVD and provide much needed new insight into the determinants of T2D and CVD in SA populations. The results will inform development of effective personalised, policy based, environmental and public health interventions.\n\nTheme 2. Digital interventions for prevention of T2D and CVD in South Asians.\n\nOur Non-Communicable Diseases (NCD) Surveillance study reveals that >30% of SAs have established diabetes or CVD and that a further >30% have obesity, prediabetes or are at high CVD risk. Quality of care is poor and there is major inequality between socio-demographic groups. Our programme of digital health research aims to understand how technology platforms can be used to improve prevention of diabetes and CVD in SA in a scalable, sustainable and equitable fashion. \n\nInformed by the results of the trial data, we will make digital interventions available for wider use by community users and healthcare providers. In collaboration with the theme 3 work strand, we will use trial data to build decision trees that help prioritise the applications to people who will benefit most. The decision support algorithms will be incorporated into the theme 3 community-facing ‘Health hub’ as a demonstration of a scalable model for integrated end-end digital care co-ordination.\n\nTheme 3. Accelerating the digital transformation of NCD management in South Asia\n \nDigital technologies offer the potential to transform primary healthcare (PHC) systems in LMICs and improve both access to and quality of healthcare. The emergence of the COVID-19 pandemic has intensified the need for digital technologies to support decentralised NCD care.\n\nWe will advance understanding of how digital platforms can be used to strengthen prevention and control of T2D, CVD and their risk factors in SA.\n\nOur PHC collaborators in Bangladesh and Sri Lanka are already committed to strengthening health information systems for PHC teams and are working to national solutions. We will bring learnings from demonstration projects to support these efforts and scale up the digital care coordination tools we have developed. This will be facilitated by the implementation toolkits and inter-operable frameworks we will establish in conjunction with the WHO. Successful demonstration projects will thus lead to a high likelihood of sustainable scale-up of our digital training and care-co-ordination modules.\n\nTheme 4: Policy and environmental interventions for primary prevention of NCDs\n\nAmong the most important actions to reverse the epidemics of T2D and CVD are to understand the built environment around people’s everyday life and to develop population-based interventions. Published evidence to support the effectiveness of policy and environmental interventions for improving health behaviours and prevention of cardio-metabolic disease comes mainly from high-income countries. It remains unclear whether such ‘whole of society’ approaches are acceptable, feasible or effective in SA settings, where resources are limited, the priorities of individuals are different, and the burden of disease is high and increasing.\nOur overarching goal is to implement and evaluate a community-based intervention for prevention of T2D and CVD, at national scale in Sri Lanka, and to provide evidence that other countries in SA can learn from in.\nThe insights from the research will be used to develop policy recommendations in South Asian countries for health promotion and prevention of T2D and CVD.. Theme 1. We will advance understanding of the lifestyle, environmental and molecular factors influencing T2D and CVD in South Asia. We will:\n1.\tAscertain health outcomes over four years for the ~150,000 South Asian men and women participating in our NCD Surveillance study, to identify new onset CVD and T2D\n2.\tcarry out molecular profiling of the baseline samples, including lipid profile and other measures of metabolic risk, and genome-wide genotyping with whole exome sequencing.\n3.\tanalyse the data to determine the age- and gender-specific incidence for T2D and CVD amongst South Asians in different settings; identify the behavioural, environmental and genomic exposures that underlie T2D and CVD in South Asians; strengthen approaches for identification of South Asian individuals and communities who are at increased risk for CVD\n\nTheme 2. We will test whether digital intervention with AI driven education or gamification for behaviour change reduces weight (primary endpoint) and improves quantitative measures of cardiometabolic health, amongst South Asian men and women aged 30-60 years with overweight or obesity, compared to usual care over 2 years.\n\nTheme 3. We will advance understanding of how digital platforms can be used to strengthen prevention and control of T2D, CVD and their risk factors, in South Asia. \n\nWe align with the Principles for Digital Development and collaborate with WHO. We will:\n1.\tadapt our ‘Co-ordinate’ platform for use in wider South Asians settings. Extend functionality to include digital training and to empower self-management by community users\n2.\tdemonstrate and evaluate platform performance in diverse South Asian settings to provide objective assessment of utility for care co-ordination\n3.\tmodularise and generalise the platform, align to global digital health standards, and collaborate with WHO, to make our approaches available to the global health technology ecosystem\n\nTheme 4\nOur overarching goal is to implement and evaluate a community-based intervention for prevention of diabetes and cardiovascular disease, at national scale in Sri Lanka, and to provide evidence that other countries in South Asia can learn from in formulation of policy. \n\nOur specific aims are:\n1.\tcomprehensively assess drivers of health risky behaviours linked with T2D and CVD through the linkage of surveillance and exposure to the built environmental data\n2.\timplement the ‘Happy Village Plus’ intervention (including community-based and school- based components) in 75 surveillance sites across Sri Lanka and evaluate the effectiveness of the intervention using a cluster randomised trial design\n3.\tbenchmark government policies aimed at tackling NCDs in India, Pakistan and Bangladesh, applying the INFORMAS (International Network for Food and Obesity/Non-Communicable Diseases (NCDs) Research, Monitoring and Action Support) framework, extended to physical activity and tobacco policies.\n \n ID: GB-GOV-10-GHRU_2_133252\nTitle: NIHR Global Health Research Unit on Health financing for Universal Health Coverage in challenging times: leaving no-one behind\nDescription: Universal health coverage (UHC) is where all people have access to the health services they need, when and where they need them, and without financial hardship. UHC is an objective shared by countries worldwide. Many low- and middle-income countries (LMICs) have made progress towards UHC, but large challenges remain (owing to COVID-19, the current war in Ukraine, climate change related natural disasters, and other crises). At the same time, the COVID-19 pandemic has highlighted at the global level the social and economic importance of health and UHC. There is, therefore, a critical opportunity for change that we embrace in this Unit: to strengthen progress to UHC in such challenging times, using the tools and perspectives of health financing and economics.\n\nThe Unit will use these tools and perspectives to carry out in-depth, policy-relevant analyses on specific health finance-related topics, engage with communities and stakeholders, and conduct capacity building. The Unit’s research will comprise the analysis of existing data, modelling, primary data collection and policy evaluation. This will be shared across four policy themes and four cross-cutting methodological areas. The policy themes revolve around a set of national and international challenges identified through extensive stakeholder consultations: (1) raising money for health; (2) allocating money for health; (3) ensuring healthcare access for left-behind groups; and (4) the role of governance, including the interaction between the health system and other sectors. The methodological areas will feed into the policy themes by ensuring the application and development of rigorous, innovative methods to address the challenges identified. They cover (1) methods of evaluating the impact of policies, (2) the analysis of distributional (“equity”) effects, (3) ways of assessing value-for-money of the policies in question, and (4) aspects of political economy.\n\nThe collaborative research programme builds directly on the work of the University of York’s NIHR Global Health Econometrics and Economics Group (GHE2), which focussed upon Brazil, Indonesia and South Africa. For the Unit, India is included as an additional research location. These four ‘middle-income’ countries comprise nearly two billion people and 45% of the world’s population living in absolute poverty. The countries are characterised by substantial within-country economic and health inequalities, hosting large marginalised and left-behind populations (e.g. geographically-isolated populations, slum dwellers, socially marginalised castes, and ethnic or religious minorities). Understanding how to advance UHC in these contexts, and among diverse vulnerability profiles, provides significant opportunities for mutual, between-country learning and knowledge spill-over benefits to other low- and middle-income countries.\n\nThe long-term aim of the Unit is to strengthen countries’ ability to adapt health financing policies and programmes for resilient, equitable and sustained progress towards UHC. It will be achieved by the production of rigorous evidence on the key health financing and resource allocation challenges. Through the work it plans to do over a five year period, the Unit aims to inform national and international policy agendas, in particular to support national and regional governments in Brazil, India, Indonesia and South Africa in developing, implementing and evaluating health financing reforms, with a view to accelerating progress towards UHC.. 1)Produce policy-relevant, actionable research, applying and developing innovative health economics methods to address major health financing challenges that impede UHC progress.\n2)Strengthen and expand research capability in using health economics/financing for decision-making in partner countries among both academic researchers and policy practitioners (including via south-south knowledge exchange network).\n3)Strengthen and develop stakeholder coalitions with policymakers, civil society partners and the public in partner countries to improve the relevance and quality of policymaking in health financing, and foster a greater use of health economic evidence in decision-making.\n4)Engage with international organisations / stakeholders / policymakers (e.g. WHO, PAHO, the World Bank, bilateral donors) to share findings, foster global uptake and influence global UHC policies.\n \n ID: GB-GOV-10-GHRU_2_133307\nTitle: NIHR Global Health Research Unit on Genomics and enabling data for Surveillance of Antimicrobial Resistance\nDescription: Antimicrobial resistant (AMR) bacterial infections are a rising global cause for concern. AMR is increasingly being predicted to significantly affect health and wellbeing on an international scale, and new technologies and greater understanding are required to reduce resistance to effective treatments. Monitoring how AMR progresses and increasing our understanding into how, when and where AMR emerges are essential to respond to the growing crisis and assess how effective local, national and international interventions are. Whole Genome Sequencing (WGS) is a technology becoming more frequently used in public health communities and offers the ability to provide information at an individual level, as well as at a regional, national and international scale due to its digital nature. Using this surveillance combined with rapid data reporting, will strengthen the evidence base of research, which is crucial for public health decision makers and their capacity to respond. Progress is being made in technical support for practical uses. However, the remaining major problem is how to rapidly and routinely link data and its interpretation to provide the greatest value at all levels.\n\nOur global multi-institutional partnership unit brings together established collaborations between the UK (Centre of Pathogen Genomic Surveillance -CGPS, Oxford University), Philippines (Research Institute for Tropical Medicine - RITM), Ibadan (University of Ibadan), India (KIMS Hospital and Research Centre) and Colombia (Colombian Agriculture Research Corporation AGROSAVIA) to continue to combat this growing problem. Capacity for WGS of AMR at each key site has been established or embedded into developing and existing national surveillance initiatives and has already helped outbreak detection and tracking of AMR populations. Building upon this foundation, the data landscape now needs to be put into use to guide public health policies and practices.\n\nThrough our partnerships we aim to reduce AMR bacterial infections through bettering WGS and surveillance across each site. Our main goals and objectives are detailed below.\n\nThe project will leave a legacy of engineering, data science and data driven surveillance by using WGS and achieving the highest value of the data on policy. It will have a direct impact on patient lives and well-being and the prevention of infection at a very local level, with a strong focus on capacity building. Outputs will highly impact public health strategies for reducing the impact of AMR in our fight against infectious diseases and infection control to curb the threat of AMR.. (1) Country Specific: To operationalise a data-driven WGS-enhanced surveillance model for priority AMR pathogens\ni) Increase capacity at sentinel sites in Nigeria for WGS-enhanced surveillance to progress an emergent national public health surveillance system \nii) Enhance detection and ceasing of hospital outbreaks in real-time by operationalising local and governmental stakeholder delivery in the Philippines\niii) Embed data-enhanced surveillance across OneHealth sectors with stakeholder reporting in Colombia\niv) Deliver reporting and enhanced surveillance for monitoring interventions (eg vaccines) in India\nv) The UK will collaboratively develop, test and validate work packages with country sites and transfer capacity for data science/engineering while optimising additional technical support for WGS and training.\n\n(2) Research: Deliver transformational capacity for data engineering, data-driven sampling strategies and technological advances in response to analysis of information architecture and stakeholder needs\ni) Model national data landscapes across all countries to identify common practice, bottlenecks, and develop an architectural plan within which to enhance surveillance\nii) Develop a stakeholder landscape and reporting framework for key local, national and international infection prevention and antimicrobial policy questions.\niii) Transform the collection, linkage, interpretation and reporting of data to stakeholders via training and deployment of data science and engineering methods and tools.\niv) Develop a rational sampling framework for surveillance and targeted outbreak investigation through leveraging routinely collected laboratory AMR data to intelligently prioritise and maximise the value of WGS.\niv) Innovate novel solutions to enhance data and WGS driven surveillance for rollout in country and regionally.\n\n(3) Implementation: Support regional networks in developing laboratory, bioinformatic, data and institutional capacity to build, maintain and sustain WGS-enhanced AMR surveillance.\ni) Optimise and minituarise standardised laboratory process for microbiological and multiple sequencing technologies for operational use across surveillance networks\nii) Optimise and support local ownership of bioinformatics for assaying risk from genomic data and contextualising within the global landscape\niii) Transfer capacity and ownership of expertise in data science and engineering to equip networks to rapidly deploy data solutions and implement the delivery of research for action\niv) Enhance institutional financial and grant management to conduit practice and sustainability.\n\n(4) Regional Centres of Excellence: Create Regional Centres of Excellence linked to WHO for technical support and institutional capacity, building on previous genomic surveillance of AMR\n(i) Enhance regional networks through engagement, training and transfer of expertise tailored to regional priorities\n(ii) Work with national agencies, regional WHO offices and international agencies to deploy owned expertise regionally\n \n ID: GB-GOV-10-GHRU_2_133364\nTitle: NIHR Global Health Research Unit on Global Surgery: Establishing a Sustainable Network of Surgical Research \nDescription: The NIHR Global Health Research Unit on Global Surgery (GSU) initially funded in 2017, established seven surgical research Hubs (Benin, Rwanda, Ghana, India, Nigeria, Mexico, South Africa), coordinating research through more than 70 ‘spoke’ hospitals across three continents, prioritised through LMIC led Delphi processes (2016-20). \n\nIn this funding envelope we will seek excellence through a new body of prioritised primary research, equitable partnerships through transfer of research leadership to the Hubs, sustainability through new Hub-based training centres.. Research Objectives:\n1.\tGenerate randomised evidence to support sustainable expansion of surgical workforces.\n2.\tAccelerate and sustain a pipeline of research to improve outcomes after surgery in LMICs.\n3.\tDevelop evidence to create resilient surgical systems.\n4.\tGenerate evidence to support resource allocation decisions through trial and model based economic evaluation alongside the primary research.\n\nEducation and Training Objectives:\n1.\tFacilitate staged transfer of research leadership to LMIC Hub Directors.\n2.\tEstablish sustainable training in surgical research methods.\n3.\tDevelop data management and analysis capability.\n4.\tDevelop new cohort of surgical research leaders.\n5.\tFacilitate development of clinical research management teams. \n6.\tCreate and utilise sustainable South to South learning pathways.\n\nCommunity Engagement and Inclusion (CEI) Objectives:\n1.\tEstablish a flexible and sustainable LMIC led CEI steering group in each partner country.\n2.\tDevelop an LMIC led CEI strategy for research project, with an integrated South to South feedback loop.\n3.\tBespoke training through South to South learning.\n4.\tMake CEI steering group advocates for surgical research through engagement with key stakeholders (communities, relevant policy makers). \n\nImpact Objectives:\n1.\tTo connect research outputs to multiple stakeholders (patients, clinicians, policy makers).\n2.\tTo establish and maintain two-way pathways for stakeholder engagement.\n3.\tTo establish local and global pathways to policymakers.\n4.\tTo create a sustainable framework for Impact assessment around the 6 domains of healthcare quality.\n \n ID: GB-GOV-10-GHRU_2_134530\nTitle: NIHR Global Health Research Unit on Prevention of air pollution health impacts through clean energy transition in Africa: CLEAN-Air (Africa)\nDescription: Globally 3.8 billion people rely on polluting fuels (e.g. wood, charcoal, kerosene) for cooking.\nHousehold air pollution (HAP) from burning these fuels caused 2.3 million premature deaths in 2019 (more than HIV/AIDS, malaria and tuberculosis). With 695,000 premature deaths and 38 million Disability-Adjusted-Life-Years (DALYs) in 2019, Sub-Saharan Africa (SSA) bears a disproportionate fraction (30%) of the global HAP-related disease burden. To reduce the dangers of reliance on these fuels, the UN established Sustainable Development Goal 7 (SDG7) has set a deadline of 2030 for “universal access to clean, modern energy”. Unfortunately, data show that the world is not on track to meet SDG7, particularly in Sub-Saharan Africa. Increasing use of liquefied petroleum gas (LPG), a clean burning fuel with much lower air pollution than traditional fuels and wide availability, is the best short to medium term solution promoted by most countries for its rapid scale-up potential.\n\nThe NIHR CLEAN-Air(Africa) Global Health Research Unit aims to inform national strategies to help achieve SDG7 through scaled adoption of LPG for clean cooking in Kenya, Uganda, Rwanda, Tanzania and Cameroon to address the negative health, gender, environment and climate impacts from reliance on polluting cooking fuels. The Unit is a partnership of leading academic, research, health and public institutions in the UK and SSA and has an ambitious 5-year program of implementation research, capacity building and health systems strengthening across its five focus countries. 1. The Unit will establish the first Air Pollution Centre of Excellence in SSA to be located at the Kenya Medical Research Institute (KEMRI) in Nairobi. The Centre will include state-of-the-art air monitoring equipment and measuring capabilities becoming a training hub from East Africa. It will support research to elucidate relationships between exposure to HAP, acute health symptoms and respiratory disease and cardiovascular health, while also supporting the Kenyan Government in setting new air quality standards.\n\n2. The Unit will initiate a program of HAP related disease prevention (including promotion of clean household energy) leveraging expertise of community health workers (CHWs) as front-line workers in health promotion through implementation of standardised national Ministry of Health (MoH) led training of CHWs in HAP, health and prevention. This will include (i) provision of curricula/ job aids in Cameroon, Rwanda and Uganda with piloting of training, (ii) creation of a digital platform for CHW training and health surveillance to maximise reach of training and (iii) monitoring and evaluation of rollout of the training in Kenya to 140,000 CHWs, initiated as part of the CLEAN-Air(Africa) Global Health Research Group.\n\n3. To inform national policies relevant to SDG7 the Unit will collaborate with several international organisations (e.g. WHO, World Food Programme) to investigate innovations that have potential to facilitate rapid scale of LPG for clean cooking in SSA. This will comprise five randomised controlled trials to test technological (pay-as-you-cook LPG smart meters and pressure cookers), nutritional (pre-cooked, vitamin enhanced beans) and behavioural (cooking classes) innovations for addressing barriers to adoption and exclusive use of clean cooking fuel for households and schools in East Africa (Kenya, Tanzania and Rwanda). The focus on schools is novel and important with widespread reliance on wood and charcoal for cooking school meals leading to a high degree of HAP exposure for school cooks and pupils. In addition an in depth mixed-methods evaluation will be conducted of a successful social entrepreneur company in Kenya providing LPG access to rural women (over 20,000 current users) to understand their ability to facilitate microfinance for clean cooking.\n\n4. The Unit will also seek to describe hidden burdens from reliance on polluting solid fuels and kerosene for household energy including gender inequity (time poverty from fetching firewood and ill health/ lost time from cooking with these fuels through survey based research in Kenya, Rwanda and Tanzania) and the occurrence of fuel related burns/ scalds (establishment of surveillance systems at specialist hospitals and in the community in Cameroon and Uganda).\n \n ID: GB-GOV-10-GHRU_2_134702\nTitle: NIHR Global Health Research Unit on Neurodevelopment and Autism in South Asia: NAMASTE\nDescription: Global Health Research Unit: Neurodevelopment and AutisM in South ASia Treatment and Evidence (NAMASTE) is an ambitious programme which aims to develop a flexible evidenced pathway towards universal health coverage for young children with Autism, focused on four regions in South Asia. Autism a severe neurodevelopmental disability has a significant impact on a child’s developmental trajectory into adulthood with profound long-term consequences on the individual and their families. About five million families in India alone live with a young autistic child, the great majority with no access to services. Over a 10-year collaboration, Sangath, an Indian public health research not-for-profit, and the University of Manchester have carefully adapted an early intervention, tested in the UK with evidence for improving long-term autism outcomes for non-specialist delivery in South Asia. The resulting 'Parent-mediated Autism Social Communication Intervention for Non-Specialists Plus (PASS Plus)’, is the first of its kind having shown real-world effectiveness in low resource settings. Sangath has in parallel, also developed an extensive digital training and supervision platform for health workers to support non-specialist delivery of a range of psychosocial interventions. \n\nNAMASTE will extend this work, with additional collaboration with the World Health Organization’s group-delivered 'Caregiver Skills Training' (CST) for more general neuro-disability, into a comprehensive detection care pathway, which will include a novel, flexible digitally enabled, two-level screening protocol (for young children with neurodevelopmental difficulty); combined with a complimentary evidenced intervention protocol embedded in the health system where possible. NAMASTE will develop a training, research and capacity building hub across India, Sri Lanka and Nepal over 5 years. Initial workforce development will build clinical and research capacity across each country; including masters, doctoral, and post-doctoral training from the UK for future health leadership. In each region and at each stage, community partners, self-advocates and co-applicants will help co-design awareness materials and advise on tool and protocol development. Evaluation of this program will be disseminated in international scientific and policy forums. This NIHR Global Health Research Unit will generate a hub for high quality research in autism and other developmental disorders in South Asia.. 1. To develop and evaluate a stepped detection pathway for a broad range of Neurodevelopmental Disorders (NDDs) including autism. This will include a system of universal screening and surveillance for developmental delays as well as autism risk, for young children. Outcome: A community administered questionnaire which is sensitive and specific in identifying young children with neurodevelopmental disabilities including autism. 400 Public health midwives (PHM) in Sri Lanka; 155 frontline workers in India and 14 Female Community Health Volunteers (FCHV) sensitized to neurodevelopmental disorders and to administer the questionnaire.\n2. To digitize the training for non-specialist to deliver two evidenced interventions, including the World Health Organization Caregiver Skills Training (WHO-CST); and the Parent-mediated Autism Social Communication Intervention for non-Specialists Plus (PASS Plus), a developmental intervention supporting social communication for autism. The programme will develop linked competency assessments for each intervention, ensuring a scalable certification process. Outcome: 10 PHMs in Sri Lanka, 8 frontline workers in India and 4 non-specialist in Nepal trained to competency to deliver the two intervention packages. \n3. To digitize a supervision platform for the PASS Plus intervention. This digital platform will allow remote access to non-specialist delivered sessions to allow supervision and quality checks and facilitate peer supervision in groups. Outcome: A digital platform which will be evaluated for use in building and supporting peer supervision skills of non-specialist health workers in delivering the PASS Plus intervention. \n4. To develop and capacity build a training and supervision cascade to deliver both interventions. Outcome: A minimum of four Master trainers for both interventions will be established within each country team.\n5. To evaluate the effectiveness of the data pipeline from detection to intervention across the sites, using process indicators, elucidating the accuracy of the detection pathway, the engagement with the interventions being delivered and the acceptability, feasibility and quality of non-specialist delivery of the two interventions. Outcome: A scalable model for a district level service provision for young children with neurodevelopmental disorders\n6. To evaluate service use and organisational costs in the implementation areas; and developing relevant health economic quality of life outcomes. Outcome Development of joint policy briefs with government partners for dissemination and scale up of services.\n7. To develop research and clinical capacity in partnership regions coupled with an extensive postgraduate training and supervision programme. This will include four PhD students registered at the University of Manchester, and embedded within local site activity. These individuals will develop capacity in key areas of need and supported to act as a nucleus to lead future clinical research within South Asia. Additionally, six Masters courses and bespoke training and professional development activities to further build capacity within local teams. Outcome Research and clinical capacity to deliver NAMASTE objectives and to develop and sustain a South Asia Neurodevelopmental Disabilities Research Hub extending beyond the project timelines \n8. To develop a public engagement campaign through participatory and collaborative methods, to help increase the awareness of neurodevelopmental disorders and autism in the implementation communities. Outcome: A customised toolkit for each site for advocacy and awareness raising.\n \n ID: GB-GOV-10-GHRU_2_134801\nTitle: NIHR Global Health Research Unit on Social and Environmental Determinants of Health Inequalities\nDescription: Brazil and Ecuador are Latin American countries that show marked inequalities in health. Although there are many potential causes of health differences between different social groups, it is reasonable to assume that these are largely due to the social determinants of health – the conditions in which people are born, grow, work, live, age and die. At the same time, there are many environmental factors that can impact individual and population health, including the built environment and climate change. Such environmental considerations tend to have the most harmful impacts on the most deprived in society.\n\nIn an attempt to reduce the impact of social conditions such as poverty, governments sometimes have introduced policies such as providing small cash payments to or building houses for the very poor. Similarly, in an attempt to protect the environment and to mitigate their harmful effects on the conditions in which people live, governments may introduce environmental policies. While such policies may have health improvement as the primary target, they may still have a notable influence on health. Our Unit will focus on discovering whether these policies, when implemented, had any impact on health, whether they had a bigger impact on disadvantaged groups (defined by income, ethnicity, sex, geography, migrant status and deprivation), and the extent to which the health impacts have been modified by the provision and organisation of health services, particularly regarding coverage, access and quality.\n\nOver the next five years, we plan to lead globally, with particular reference to Latin America, in terms of using the full potential of existing databases by combining them to find out whether social and environmental policies have had an impact on health and health inequalities, and the extent to which these can be affected by health service provision.. 1. Building, developing and linking national databases covering health, social (e.g. welfare) and environmental registers in Brazil and Ecuador;\n2. Studying the impacts of social and environmental policies, and the effects of large scale population movement on health and health inequalities;\n3. Creating indicators of deprivation for small areas covering the whole of Brazil and Ecuador;\n4. Determining how best to organise health services to improve health for all social groups and to respond to social and environmental threats in a way that minimises the damage they do to health;\n5. Focusing on health outcomes that are considered priorities in Brazil, Ecuador and the Latin American region, in which our research team has particular expertise: non-communicable diseases including mental health and asthma; maternal and child health; reproductive and sexual health; COVID-19, infectious diseases and emerging health threats; neglected tropical diseases; and violence;\n6. Monitoring progress towards the United Nations’ 2030 Agenda for Sustainable Development (particularly Goal 3: Ensure healthy lives and promote well-being for all at all ages);\n7. Working with stakeholders, communities and the public to decide which policies we should evaluate, set priorities for our research, and tell different audiences about our results, particularly those who are making policies; and\n8. Training researchers from Brazil, Ecuador and other low and middle-income countries in global health research methods by developing a research hub in Ecuador, and providing training programmes and mechanisms to share researchers’ experiences.\n", "_version_":1864758837754462208 }] } }