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"id":"2e961a8a-fb92-418e-a5f1-36398fe52490", "related_activity_context":"ID: GB-GOV-10-RIGHT_1\nTitle: NIHR Research and Innovation for Global Health Transformation: Call 1 \nDescription: National Institute for Health and Care Research (NIHR)’s first Research and Innovation for Global Health Transformation (RIGHT) call. RIGHT funds cutting-edge interdisciplinary applied health research in key areas in in low- and middle-income countries (LMICs) where a strategic and targeted investment can result in a transformative impact.\nRIGHT Call 1 addresses research in three key areas: epilepsy, infection-related cancers and severe stigmatising skin diseases. UK universities and research institutes were invited to submit applications including a co-applicant or joint lead applicant from an LMIC relevant to the research proposal. Research must be focused on improving the health and welfare of people in LMICs. . 1. Deliver research for the primary benefit to the health and welfare of the poorest individuals living in LMICs, typically through research for the prevention of ill health and optimal disease management, in three research areas: (1) Epilepsy (2) Infection-related cancers (3) Severe stigmatising skin diseases. \n2. Strengthen capacity for research and knowledge exchange through equitable partnerships between researchers in the UK and LMICs. \n3. Promote interdisciplinary approaches to working (including, but not limited to: clinical, health economics, statistics, qualitative and social sciences), to ensure that research objectives can be delivered. \n \n ID: GB-GOV-10-RIGHT_1_200125\nTitle: NIHR RIGHT1: Improving experiences of severe stigmatising skin diseases in Ghana and Ethiopia\nDescription: A UK and low- and middle-income country (LMIC) research partnership that aims to improve outcomes for individuals with leprosy, yaws, Buruli ulcer and cutaneous leishmaniasis. The Skin Health Africa Research Programme (SHARP) is a an interdiscplinary partnership of clinicians, social scientists, epidemiologists, statisticians and laboratory scientists working with communities affected by severe stigmatising skin diseases.. To improve outcomes for people with severe stigmatising skin diseases by strengthening the care cascade through scalable strategies for earlier detection, improving management to reduce disability and counteracting stigma:\n1. to evaluate integrated community-based strategies for early diagnosis, adherence support and stigma reduction\n2. to undertake facility-based trials of dressings for Buruli ulcer\n3. to develop clinical and patient reported outcome measures for cutaneous leishmaniasis\n4. to promote collaboration and build research capacity in Ghana and Ethiopia. \n \n ID: GB-GOV-10-RIGHT_1_200129\nTitle: NIHR RIGHT1:Reducing the Burden of Severe Stigmatising Skin Diseases Through Equitable Approaches to Health Systems Strengthening\nDescription: A UK and low- and middle-income country (LMIC) research partnership that aims to reduce illness, stigma, mental distress, social exclusion and poverty caused by severe stigmatising skin diseases in Liberia.. Using a person-centred approach, evaluate, develop and adapt health systems interventions for the management of severe stigmatising skin diseases (SSSDs) in Liberia to generate learning for other settings in sub-Saharan Africa by: \n1. Identifying effective strategies to detect, refer, treat and support people living with SSSDs that are acceptable, affordable and sustainable especially amongst the most vulnerable \n2. Designing and testing innovative health systems interventions that are responsive to biomedical, psychological and social support needs by assessing persons living with SSSDs, family, and provider perspectives and priorities at different levels \n3. Enhancing quality and equity of approaches that will see all persons living with SSSDs receiving essential, effective and affordable treatment, care and support at the individual, family, community and facility level. \nAdditionally, the project will also work toward developing a strong and sustainable research infrastructure for multi-disciplinary applied health research which focuses on severe stigmatising skin diseases and associated interventions in Liberia.\n \n ID: GB-GOV-10-RIGHT_1_200132\nTitle: NIHR RIGHT1: Transforming the Treatment and Prevention of Leprosy and Buruli ulcers in Low and Middle-Income Countries (LMICs)\nDescription: A UK and low- and middle-income country (LMIC) research partnership that aims to improve care and reduce stigma and social isolation for leprosy and Buruli ulcer in Nepal, India and Nigeria.. 1. To improve self-care in the community for patients who are at risk of recurring leprosy ulcers. \n2. To better understand the needs of patients with Buruli ulcer and the barriers to meeting those needs. \n3. To develop new and improved methods of clinical care for both leprosy and Buruli ulcer patients. \n \n ID: GB-GOV-10-RIGHT_1_200133\nTitle: NIHR RIGHT1:Evaluation and Transfer of Precise Diagnosis for Improved Outcomes of Children and Young Adults with Epstein Barr Virus-driven Lymphoma\nDescription: A UK and low- and middle-income country (LMIC) research partnership that aims to test two new diagnostic technologies that can help provide fast and reliable diagnosis for Epstein-Barr virus (EBV) in sub-Saharan Africa.. 1. To test two new technologies which, by leapfrogging conventional diagnostic approaches, could bring fast and precise diagnosis of Epstein Barr Virus Lymphoma to sub-Sahara Africa; \n2. To generate viral and tumour sequence information to inform the design of future screening programmes and vaccine development; \n3. To perform a clinical validation of our diagnostic tools and then a controlled before-after study to test whether these speed up diagnosis, increase the number of children diagnosed and treated, and ultimately improve survival compared to gold-standard pathology.\n \n ID: GB-GOV-10-RIGHT_1_200134\nTitle: NIHR RIGHT1: Epilepsy Pathway Innovation in Africa (EPInA)\nDescription: A UK and low- and middle-income country (LMIC) research partnership that aims to address the diagnosis, treatment and understanding of epilepsy in Ghana, Kenya and Tanzania.. PREVENT: reduce the incidence of infection and peri-natal injury in an endemic region in Tanzania and the subsequent risk of epilepsy. \nDIAGNOSE: improve the rate of accurate diagnosis of epilepsy by developing app-based technologies. \nTREATMENT: increase the adherence to medication using text messaging. \nSOCIETAL CHANGE: ensure an enduring, positive change by improving public awareness and reducing the stigma experienced by people with epilepsy in Sub Saharan Africa. \n \n ID: GB-GOV-10-RIGHT_1_200135\nTitle: NIHR RIGHT1:Empowering People with Cutaneous Leishmaniasis Intervention Programme to Improve Patient Journey and Reduce Stigma via Community Education\nDescription: A UK and low- and middle-income country (LMIC) research partnership, Empowering people with Cutaneous Leishmaniasis: Intervention Programme to improve patient journey and reduce Stigma via community Education (ECLIPSE) is a four-year healthcare programme which aims to improve the cutaneous leishmaniasis patient journey and reduce stigma in the most marginalised and underserved communities in Brazil, Ethiopia and Sri Lanka. . 1. IMPROVE PATIENT OUTCOMES AND EMPOWER COMMUNITIES - To co-develop, implement and evaluate two interventions (community education campaigns and training packages for healthcare workers) in each Low and Middle Income Country (LMIC). \n2. FOSTER CROSS-CULTURAL LEARNING THROUGH ECLIPSE PARTNERSHIP - To establish the transcontinental ECLIPSE consortium and carry out the 4-year applied health programme, which will enhance rapid international knowledge mobilisation. \n3. INFLUENCE HEALTH POLICY - To recommend policy changes that address gaps in public health provision related to cutaneous leishmaniasis identified through the ECLIPSE research and influence implementation of these recommendations through the ECLIPSE Policy Network. \n4. ACQUIRE NEW KNOWLEDGE ON cutaneous leishmaniasis - To produce a comprehensive biopsychosocial model of cutaneous leishmaniasis embedded in the syndemics theoretical framework in three LMICs and to widely disseminate results and policy recommendations. \n5. DEVELOP SUSTAINABLE HEALTHCARE INTERVENTIONS - To ensure sustainability of interventions through collaboration with a wide range of cutaneous leishmaniasis constituents (including patients, community stakeholders, healthcare practitioners and policy makers) who have the ability and motivation to advocate for the routine implementation of ECLIPSE interventions and recommend new strategies in cutaneous leishmaniasis-endemic regions at national and international level. \n6. APPLIED HEALTH AND CL RESEARCH CAPACITY BUILDING - To establish a cohort of 18 early career researchers and ensure their onward employability and retention through a robust interdisciplinary training and mentorship programme, in addition to enhancing leadership skills of senior ECLIPSE researchers to sustain the newly formed research groups.\n \n ID: GB-GOV-10-RIGHT_1_200140\nTitle: NIHR RIGHT1: Social Sciences for Severe Stigmatising Skin Diseases (the 5-S Foundation)\nDescription: A UK and low- and middle-income country (LMIC) research partnership, Social Sciences for Severe Stigmatising Skin Diseases (5S) Foundation aims to fill gaps between knowledge, treatment and practice around three diseases, podoconiosis, mycetoma and scabies, working in Ethiopia, Sudan and Rwanda.. 1. To examine the cultural logics and social and economic contexts of podoconiosis, mycetoma and scabies;\n2. To understand the dynamics and dimensions of stigma;\n3. To investigate how all three diseases have been conceptualised at national and international policy levels;\n4. To evaluate existing interventions using social science perspectives;\n5. To refine the conceptual framework developed to guide the Foundation’s research;\n6. To develop a comprehensive intervention strategy for each disease;\n7. To support endemic-country training posts (PhD and postdoctoral) in a manner that will leave enduring capacity or social science research;\n8. To facilitate South-South and North-South sharing of best practice in research and advocacy applicable to a wide range of stigmatising conditions in low-resource settings.\n \n ID: GB-GOV-10-RIGHT_1_200144\nTitle: NIHR RIGHT1: Prevention of epilepsy from birth-related brain injury\nDescription: A UK and low- and middle-income country (LMIC) partnership that aims to examine if a simple, pragmatic, and evidenced-based intrapartum care bundle for labour involving birth companions and empowering mothers will reduce perinatal brain injury and thus prevent epilepsy in India.. 1. To examine if a pragmatic and evidenced-based intrapartum care bundle involving birth companions and empowering mothers will reduce birth injury related epilepsy at 18 months of age in India. \n2. If effective, incorporate care bundle into the Labour Room Quality Improvement (LaQshya) programme, for national implementation, thus averting approximately 50,000 epilepsy cases every year in India. \n3. Provide opportunities for academic and clinical capacity building in India in midwifery, neonatal/paediatric neurology and epilepsy, and public health. \n \n ID: GB-GOV-10-RIGHT_1_PPDA\nTitle: Proposal and Partnership Development Awards (PPDA) for NIHR Research and Innovation for Global Health Transformation (RIGHT) call 1 Stage 2 applicants\nDescription: The purpose of Proposal and Partnership Development Awards (PPDA) funding is to improve the quality and likelihood of success of the projects funded through the NIHR Research and Innovation for Global Health Transformation (RIGHT) programme. Applicants that are successful at RIGHT Stage 1 and invited to submit a Stage 2 application are eligible for a PPDA, subject to satisfactory submission of a PPDA application. Not all Stage 2 applicants awarded a PPDA go on to secure RIGHT programme funding, therefore the details of PPDA recipients are not published. For RIGHT Call 1, PPDA were extended to 13 applicant organisations to support partnership development and the preparation of a RIGHT Stage 2 application.. Proposal and Partnership Development Awards (PPDA) provide funding of up to £10,000 for organisations applying to NIHR Research and Innovation for Global Health Transformation (RIGHT) programme funding to:\n1.\tSupport applicants to work collaboratively with all study partners to develop the stage 2 application\n2.\tEnhance partnerships across the proposed research collaboration\n3.\tInitiate preparation of study governance documentation (i.e. due diligence and finance assurance policies)\nPPDA funds must be spent between the notification of RIGHT stage 1 outcome and the submission of the RIGHT stage 2 application.\n", "_version_":1866661297626546176 }] } }