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      "related_activity_context":"ID: GB-GOV-10-RIGHT_6\nTitle: NIHR Research and Innovation for Global Health Transformation: Call 6\nDescription: National Institute for Health and Care Research (NIHR)'s sixth Research and Innovation for Global Health Transformation (RIGHT) call. RIGHT funds cutting-edge interdisciplinary applied health research in key areas in low- and middle-income countries (LMICs) where a strategic and targeted investment can result in a transformative impact. \nRIGHT Call 6 supports equitable partnerships between researchers to generate new research knowledge and evidence on interventions to improve prevention, treatment, and management of multiple long-term conditions in ODA-eligible countries. \nUK and LMIC-based universities and research institutes were invited to submit applications. Research must be focused on improving the health and welfare of people in LMICs.  . The aims of NIHR RIGHT Call 6 are to:\n1. Deliver applied health research for the direct and primary benefit to the health and wealth of people living in ODA-eligible countries, with a focus on preventing, treating, and managing multiple long-term conditions. \n2. Strengthen capacity for research and knowledge exchange through equitable partnerships between researchers and institutions involved in the research.\n3. Promote interdisciplinary approaches to working (including, but not limited to: clinical medicine, health economics, statistics, qualitative and social sciences), to ensure that research objectives can be delivered. \n4. Generate new research knowledge and evidence on interventions to improve health outcomes of people in LMICs.\n \n ID: GB-GOV-10-RIGHT_6_205540\nTitle: NIHR RIGHT 6: Affordable Cardiac Rehabilitation: An Outreach Inter-disciplinary Strategic Study (ACROSS)\nDescription: A UK and low- and middle-income country (LMIC) research partnership between the University of Glasgow and Ishrat Husain Pakistan Institute of Living and Learning that aims to develop an affordable home-based rehabilitation programme for people with long term conditions including heart disease and mental health conditions in Bangladesh, Pakistan and India. \n\nBeginning in July 2025, the five-year project intends to build on existing research collaborations in South Asia to address the unmet needs of heart disease and mental health multimorbidity in South Asia. Home-based programmes provide an affordable model of delivery that can leverage a scalable increase in rehabilitation access in LMICs, a key strategic global goal of the World Health Organisation. The project aims to do this through the evaluation and implementation of a sustainable, cultural, and contextually appropriate model of home-based rehabilitation for people with multimorbidity that includes heart disease and a mental health disorder that is both affordable and scalable. . The award has five objectives: \n\n1. To co-design with key stakeholders a culturally and contextually adapted, affordable home-based rehabilitation (‘ACROSS’) programme with low intensity inventions for depression and anxiety (Work Package 1).\n2. To co-design ACROSS delivery training for health professionals to include a train-the-trainer programme to enable the cascade of training (Work Package 1).\n3. To assess the feasibility and acceptability of the implementation of ACROSS programme as well as trial design and examine the parameters and processes of a full-scale trial, including recruitment, randomisation, and retention (Work Package 2).\n4. To determine clinical effectiveness (hierarchical primary outcome of mortality, hospital admission, and health-related of quality life) of the ACROSS programme (Work Package 3).\n5. To determine cost-effectiveness of ACROSS programme in terms of an incremental cost per quality adjusted life year (Work Package 3).\n \n ID: GB-GOV-10-RIGHT_6_205554\nTitle: NIHR RIGHT 6: Digitally integrated care pathways for multiple long-term conditions in Sri Lanka\nDescription: A UK and low-and-middle-income country (LMIC) research partnership between the University of Birmingham and the University of Jaffna, Sri Lanka which aims to improve the management of multiple long-term conditions (MLTC) in primary care in Sri Lanka. \n\nIn Sri Lanka, many people suffer from diabetes, high blood pressure, heart disease, kidney disease, and mental health conditions. When someone has several long-term conditions, it becomes more difficult to manage their care, leading to poor health outcomes. Commencing in July 2024, the five-year project intends to use the team's previous trial experience and evaluation of complex digital healthcare implementations in the region to develop, implement and evaluate a digitally integrated care pathway within electronic health records. This will be done to manage primary care patients with MLTC in Sri Lanka. The electronic patient record systems in primary care centres will be used to create an improved care plan for those with MLTC in order to standardise care and improve the patient experience using digital technologies. . The project has six objectives:\n1. To establish a stakeholder consultation group (SCG) consisting of people living with Multiple Long-Term-Conditions (MLTC), healthcare professionals, clinical informaticians, policy makers and researchers to provide expertise throughout the research lifecycle.                                                                                                                                                                                                                                       2. To evaluate existing care pathways and clinical guidelines and identify stakeholder priorities for improvement.\n3. To develop and implement a stakeholder designed Digitally Integrated Care Pathway (DICP).\n4. To evaluate the DICP through a cluster randomised controlled trial.                                                                                                                                                                                                                 \n5. To evaluate the contextual and organisational factors that may influence scalability and transferability of the DICP across Sri Lanka and countries with similar population and health systems.\n6. To carry out an economic evaluation of the DICP. \n \n ID: GB-GOV-10-RIGHT_6_205556\nTitle: NIHR RIGHT 6: Co-morbid long-term disease management in the Americas: a blended intervention (COLMA)\n\nDescription: A UK and low-and-middle-income countries (LMICs) research partnership between King’s College London and Scientific University of the South (Universidad Científica del Sur), Peru.\n\nDepression, hypertension, and diabetes are the three biggest health problems in Peru, Argentina, and across Latin American countries (LACs). These long-term conditions often present together, posing a challenge and an opportunity to integrate an effective and common treatment in LACs and elsewhere. Health care for people with chronic problems is often limited, disjointed, and of low quality, among other things because there is a dearth of medical doctors and psychologists. Commencing in July 2024, the five-year project intends to use the team’s previous research, on technology and community resources to support the treatment of depression, hypertension, and diabetes, to develop more powerful and integrated effective components to manage comorbidity. Planned research activities aim to improve the health and quality of life of low-income people with comorbid depression, hypertension and/or diabetes in Peru and Argentina.. The project has five objectives:\n1. Develop and evaluate the effectiveness, cost-effectiveness, and implementation of a technology-supported intervention for people with comorbid depression, hypertension, and/or diabetes attending primary care clinics in low-income communities in Argentina and Peru. \n2. Better understand the settings and needs of those with and those involved in the management of chronic comorbid conditions and identify appropriate strategies to effectively implement the intervention to increase its chances of successful adoption.  \n3. Adapt previously tried treatments or develop new treatments, when unavailable, in close collaboration with local stakeholders. \n4. Evaluate clinical gains and costs of successfully implementing this intervention among people with comorbid depression, hypertension, and/or diabetes in Peru and Argentina.\n5. Deliver a robust training programme for researchers and community members in Argentina and Peru and an extended network in Latin American countries.\n\n \n ID: GB-GOV-10-RIGHT_6_205561\nTitle: NIHR RIGHT 6: Integrated psychosocial care plan for comorbid depression in breast cancer patients in low-resource settings\nDescription: A partnership led by the Pakistan Institute of Living and Learning, and the University of Sheffield aims to develop, implement, and evaluate a culturally adapted prevention and integrated psychosocial care plan for depressed breast cancer survivors that can be implemented across low-resource settings. \n\nBreast cancer is one of the main causes of death in women across the world every year.  Pakistan has the highest rate of breast cancer in women in South Asia. The unavailability of and costly self-paid breast cancer treatment adds to increasing significant distress among women, with women who do survive having higher levels of depression and anxiety. This impacts their treatment outcomes and increases chances of the cancer returning. Beginning in July 2024, the five-year project aims to improve the well-being of breast cancer survivors as well as promote awareness to assist with increasing chances of early detection. This award is built on earlier work: Moving on After Breast Cancer Plus (Moving on ABC Plus) in Pakistan, and intends to assess different methods of offering support through mental health care plans or a combination of treatments in survivors of breast cancer with depression in Pakistan. Research activities include the development and application of a suitable mental health care plan for women survivors of breast cancer in Pakistan.. The project has six objectives:\n1. Develop and apply a suitable mental health care plan for women survivors of breast cancer in Pakistan (Workstream One).\n2. Work with policy makers, patients, families, and other professionals to understand their views on how to make the mental health care plan available for all survivors (Workstream Two).\n3. To understand the cost of breast cancer and depression in Pakistan and assess the cost-effectiveness of the proposed intervention (Workstream Three).\n4. Develop a social media campaign to increase public awareness to help reduce the rate of breast cancer and bolster the identification of early symptoms (Workstream Four).\n5. Train researchers and healthcare professionals in breast cancer research and ways of providing mental health support (Workstream Five).\n6. Set up a system to collect information about people with breast cancer in Sindh Province, Pakistan (Workstream Six). \n \n ID: GB-GOV-10-RIGHT_6_205601\nTitle: NIHR RIGHT 6: Smoking cessation for people with severe mental illness in South Asia (SCIMITAR-SA)\nDescription: A UK and low- and middle-income country (LMICs) research partnership, between The University of York and the National Institute of Mental Health and Neurosciences, India.\n\nPeople with severe mental illness constitute one of the most vulnerable populations, with a life expectancy that is reduced by approximately 20 years. Much of this reduced life expectancy is driven by the development of multiple long-term conditions (MLTCs) in these populations. The greatest contributor to this inequality is the use of tobacco, and addressing this problem can result in the greatest health gains for people with severe mental illness. Beginning in July 2024, the four year programme will adapt and refine a treatment for tobacco use by people with severe mental illness in Bangladesh, India and Pakistan. The award will use valid and reliable tests to assess the success of the intervention before assessing the economic benefits of the treatment and identifying strategies which are most useful in delivering the treatment in mental health facilities.. The project has six objectives:\n1. Develop and apply a suitable mental health care plan for women survivors of breast cancer in Pakistan (Workstream One).\n2. Work with policy makers, patients, families, and other professionals to understand their views on how to make the mental health care plan available for all survivors (Workstream Two).\n3. To understand the cost of breast cancer and depression in Pakistan and assess the cost-effectiveness of the proposed intervention (Workstream Three).\n4. Develop a social media campaign to increase public awareness to help reduce the rate of breast cancer and bolster the identification of early symptoms (Workstream Four).\n5. Train researchers and healthcare professionals in breast cancer research and ways of providing mental health support (Workstream Five).\n6. Set up a system to collect information about people with breast cancer in Sindh Province, Pakistan (Workstream Six). \n \n ID: GB-GOV-10-RIGHT_6_PPDA\nTitle: Proposal and Partnership Development Awards (PPDA) for NIHR Research and Innovation for Global Health Transformation (RIGHT) call 6 Stage 2 applicants\nDescription: The purpose of Proposal and Partnership Development Awards (PPDA) funding is to improve the quality and likelihood of success of the projects funded through the NIHR Research and Innovation for Global Health Transformation (RIGHT) programme. Applicants that are successful at RIGHT Stage 1 and invited to submit a Stage 2 application are eligible for a PPDA, subject to satisfactory submission of a PPDA application. Not all Stage 2 applicants awarded a PPDA go on to secure RIGHT programme funding, therefore the details of PPDA recipients are not published. For RIGHT Call 6, PPDA were extended to 12 applicant organisations to support partnership development and the preparation of a RIGHT Stage 2 application.. Proposal and Partnership Development Awards (PPDA) provide funding of up to £10,000 for organisations applying to NIHR Research and Innovation for Global Health Transformation (RIGHT) programme funding to:\n1.\tSupport applicants to work collaboratively with all study partners to develop the stage 2 application\n2.\tEnhance partnerships across the proposed research collaboration\n3.\tInitiate preparation of study governance documentation (i.e. due diligence and finance assurance policies)\nPPDA funds must be spent between the notification of RIGHT stage 1 outcome and the submission of the RIGHT stage 2 application.\n",
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