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      "last-updated-datetime":"2026-02-13T18:59:49Z",
      "last_updated_datetime":"Fri Feb 13 18:59:49 UTC 2026",
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      "reporting_org_ref":"XM-DAC-301-2",
      "reporting-org.narrative":["International Development Research Centre","Centre de recherches pour le développement international","Centro Internacional de Investigaciones para el Desarrollo"],
      "reporting_org_narrative":["International Development Research Centre","Centre de recherches pour le développement international","Centro Internacional de Investigaciones para el Desarrollo"],
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      "title.narrative":["Bacteriocins as an innovative antimicrobial solution for the reduction of antibiotic use in the avian sector","Les bactériocines comme solution antimicrobienne innovante pour la réduction de l’usage des antibiotiques dans le secteur aviaire"],
      "title_narrative":["Bacteriocins as an innovative antimicrobial solution for the reduction of antibiotic use in the avian sector","Les bactériocines comme solution antimicrobienne innovante pour la réduction de l’usage des antibiotiques dans le secteur aviaire"],
      "title_narrative_text":["Bacteriocins as an innovative antimicrobial solution for the reduction of antibiotic use in the avian sector","Les bactériocines comme solution antimicrobienne innovante pour la réduction de l’usage des antibiotiques dans le secteur aviaire"],
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      "description.narrative":["The poultry industry is one of the most promising economic sectors worldwide, including in low- and moderate-income countries like Tunisia. However, poultry farms are subject to a variety of diseases that can lead to considerable economic losses and major consequences for animal and human health. Further, the overuse of antibiotics has led to a worrying increase in the number of multi-resistant bacteria. In addition, the impact of poultry farms on the environment, food safety and animal protection and welfare issues are now part of consumer demands which need to be considered. \n\nThe first phase of the AviBiocin I project was to assess the potential of bacteriocins (proteins produced by bacteria of one strain and active against those of a closely related strain) as an alternative to antibiotics in the Tunisian poultry industry. This project isolated, characterized and demonstrated the efficacy of certain bacteriocins and assessed their safety, bioavailability and impact. The project also developed eco-responsible technological processes for the pilot production of active bacteriocins. Finally, the prophylactic and therapeutic potential of bacteriocins was demonstrated in experimental poultry houses, through trials in broiler chickens. These trials confirmed the efficacy of bacteriocins under rearing conditions. \n\nIn the second phase of this project, these original, unique and highly promising results will be confirmed on an industrial scale under real poultry farming conditions in Tunisia. It will be funded through InnoVet-AMR 2.0, a four-year partnership between IDRC and the United Kingdom’s Department of Health and Social Care. The initiative is aimed at reducing the emerging risk that anti-microbial resistance in animals poses to global health and food security.\n","L’industrie avicole est l’un des secteurs économiques les plus prometteurs au monde, y compris dans les pays à faible revenu et à revenu intermédiaire comme la Tunisie. Cependant, les élevages de volailles sont confrontés à toute une variété de maladies qui peuvent entraîner des pertes économiques considérables et avoir des conséquences majeures sur la santé animale et humaine. En outre, l’utilisation excessive d’antibiotiques a entraîné une augmentation inquiétante du nombre de bactéries multirésistantes. En outre, les répercussions des élevages de volailles sur l’environnement, la sécurité alimentaire et les questions de protection et de bien-être des animaux font désormais partie des exigences des consommatrices et consommateurs qui doivent être prises en compte. \n\nLa première phase du projet AviBiocin I consistait à évaluer le potentiel des bactériocines (protéines produites par les bactéries d’une souche et actives contre celles d’une souche étroitement apparentée) comme solution de rechange aux antibiotiques dans l’industrie avicole tunisienne. Ce projet a permis d’isoler, de caractériser et de démontrer l’efficacité de certaines bactériocines et d’évaluer leur sécurité, leur biodisponibilité, ainsi que leurs répercussions. Le projet a également permis d’élaborer des procédés technologiques écoresponsables pour la production pilote de bactériocines actives. Enfin, le potentiel prophylactique et thérapeutique des bactériocines a été démontré dans des poulaillers expérimentaux, au moyen d’essais sur des poulets de chair. Ces essais ont confirmé l’efficacité des bactériocines dans le cadre de conditions d’élevage. \n\nDans la deuxième phase de ce projet, ces résultats originaux, uniques et très prometteurs seront confirmés à l’échelle industrielle dans des conditions réelles d’élevage de volailles en Tunisie. Il sera financé dans le cadre de l’initiative Solutions vétérinaires innovatrices pour la résistance aux antimicrobiens 2.0 (InnoVet-AMR 2.0), un partenariat de quatre ans entre le CRDI et le Department of Health and Social Care du Royaume-Uni. Cette initiative vise à réduire les risques émergents que pose la résistance aux antimicrobiens chez les animaux pour la santé mondiale et la sécurité alimentaire."],
      "description_narrative":["The poultry industry is one of the most promising economic sectors worldwide, including in low- and moderate-income countries like Tunisia. However, poultry farms are subject to a variety of diseases that can lead to considerable economic losses and major consequences for animal and human health. Further, the overuse of antibiotics has led to a worrying increase in the number of multi-resistant bacteria. In addition, the impact of poultry farms on the environment, food safety and animal protection and welfare issues are now part of consumer demands which need to be considered. \n\nThe first phase of the AviBiocin I project was to assess the potential of bacteriocins (proteins produced by bacteria of one strain and active against those of a closely related strain) as an alternative to antibiotics in the Tunisian poultry industry. This project isolated, characterized and demonstrated the efficacy of certain bacteriocins and assessed their safety, bioavailability and impact. The project also developed eco-responsible technological processes for the pilot production of active bacteriocins. Finally, the prophylactic and therapeutic potential of bacteriocins was demonstrated in experimental poultry houses, through trials in broiler chickens. These trials confirmed the efficacy of bacteriocins under rearing conditions. \n\nIn the second phase of this project, these original, unique and highly promising results will be confirmed on an industrial scale under real poultry farming conditions in Tunisia. It will be funded through InnoVet-AMR 2.0, a four-year partnership between IDRC and the United Kingdom’s Department of Health and Social Care. The initiative is aimed at reducing the emerging risk that anti-microbial resistance in animals poses to global health and food security.\n","L’industrie avicole est l’un des secteurs économiques les plus prometteurs au monde, y compris dans les pays à faible revenu et à revenu intermédiaire comme la Tunisie. Cependant, les élevages de volailles sont confrontés à toute une variété de maladies qui peuvent entraîner des pertes économiques considérables et avoir des conséquences majeures sur la santé animale et humaine. En outre, l’utilisation excessive d’antibiotiques a entraîné une augmentation inquiétante du nombre de bactéries multirésistantes. En outre, les répercussions des élevages de volailles sur l’environnement, la sécurité alimentaire et les questions de protection et de bien-être des animaux font désormais partie des exigences des consommatrices et consommateurs qui doivent être prises en compte. \n\nLa première phase du projet AviBiocin I consistait à évaluer le potentiel des bactériocines (protéines produites par les bactéries d’une souche et actives contre celles d’une souche étroitement apparentée) comme solution de rechange aux antibiotiques dans l’industrie avicole tunisienne. Ce projet a permis d’isoler, de caractériser et de démontrer l’efficacité de certaines bactériocines et d’évaluer leur sécurité, leur biodisponibilité, ainsi que leurs répercussions. Le projet a également permis d’élaborer des procédés technologiques écoresponsables pour la production pilote de bactériocines actives. Enfin, le potentiel prophylactique et thérapeutique des bactériocines a été démontré dans des poulaillers expérimentaux, au moyen d’essais sur des poulets de chair. Ces essais ont confirmé l’efficacité des bactériocines dans le cadre de conditions d’élevage. \n\nDans la deuxième phase de ce projet, ces résultats originaux, uniques et très prometteurs seront confirmés à l’échelle industrielle dans des conditions réelles d’élevage de volailles en Tunisie. Il sera financé dans le cadre de l’initiative Solutions vétérinaires innovatrices pour la résistance aux antimicrobiens 2.0 (InnoVet-AMR 2.0), un partenariat de quatre ans entre le CRDI et le Department of Health and Social Care du Royaume-Uni. Cette initiative vise à réduire les risques émergents que pose la résistance aux antimicrobiens chez les animaux pour la santé mondiale et la sécurité alimentaire."],
      "description_narrative_text":["The poultry industry is one of the most promising economic sectors worldwide, including in low- and moderate-income countries like Tunisia. However, poultry farms are subject to a variety of diseases that can lead to considerable economic losses and major consequences for animal and human health. Further, the overuse of antibiotics has led to a worrying increase in the number of multi-resistant bacteria. In addition, the impact of poultry farms on the environment, food safety and animal protection and welfare issues are now part of consumer demands which need to be considered. \n\nThe first phase of the AviBiocin I project was to assess the potential of bacteriocins (proteins produced by bacteria of one strain and active against those of a closely related strain) as an alternative to antibiotics in the Tunisian poultry industry. This project isolated, characterized and demonstrated the efficacy of certain bacteriocins and assessed their safety, bioavailability and impact. The project also developed eco-responsible technological processes for the pilot production of active bacteriocins. Finally, the prophylactic and therapeutic potential of bacteriocins was demonstrated in experimental poultry houses, through trials in broiler chickens. These trials confirmed the efficacy of bacteriocins under rearing conditions. \n\nIn the second phase of this project, these original, unique and highly promising results will be confirmed on an industrial scale under real poultry farming conditions in Tunisia. It will be funded through InnoVet-AMR 2.0, a four-year partnership between IDRC and the United Kingdom’s Department of Health and Social Care. The initiative is aimed at reducing the emerging risk that anti-microbial resistance in animals poses to global health and food security.\n","L’industrie avicole est l’un des secteurs économiques les plus prometteurs au monde, y compris dans les pays à faible revenu et à revenu intermédiaire comme la Tunisie. Cependant, les élevages de volailles sont confrontés à toute une variété de maladies qui peuvent entraîner des pertes économiques considérables et avoir des conséquences majeures sur la santé animale et humaine. En outre, l’utilisation excessive d’antibiotiques a entraîné une augmentation inquiétante du nombre de bactéries multirésistantes. En outre, les répercussions des élevages de volailles sur l’environnement, la sécurité alimentaire et les questions de protection et de bien-être des animaux font désormais partie des exigences des consommatrices et consommateurs qui doivent être prises en compte. \n\nLa première phase du projet AviBiocin I consistait à évaluer le potentiel des bactériocines (protéines produites par les bactéries d’une souche et actives contre celles d’une souche étroitement apparentée) comme solution de rechange aux antibiotiques dans l’industrie avicole tunisienne. Ce projet a permis d’isoler, de caractériser et de démontrer l’efficacité de certaines bactériocines et d’évaluer leur sécurité, leur biodisponibilité, ainsi que leurs répercussions. Le projet a également permis d’élaborer des procédés technologiques écoresponsables pour la production pilote de bactériocines actives. Enfin, le potentiel prophylactique et thérapeutique des bactériocines a été démontré dans des poulaillers expérimentaux, au moyen d’essais sur des poulets de chair. Ces essais ont confirmé l’efficacité des bactériocines dans le cadre de conditions d’élevage. \n\nDans la deuxième phase de ce projet, ces résultats originaux, uniques et très prometteurs seront confirmés à l’échelle industrielle dans des conditions réelles d’élevage de volailles en Tunisie. Il sera financé dans le cadre de l’initiative Solutions vétérinaires innovatrices pour la résistance aux antimicrobiens 2.0 (InnoVet-AMR 2.0), un partenariat de quatre ans entre le CRDI et le Department of Health and Social Care du Royaume-Uni. Cette initiative vise à réduire les risques émergents que pose la résistance aux antimicrobiens chez les animaux pour la santé mondiale et la sécurité alimentaire."],
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      "json.title":"{\"narrative\": [\"Bacteriocins as an innovative antimicrobial solution for the reduction of antibiotic use in the avian sector\", \"Les bact\\u00e9riocines comme solution antimicrobienne innovante pour la r\\u00e9duction de l\\u2019usage des antibiotiques dans le secteur aviaire\"], \"narrative.currency\": [], \"narrative.value_date\": [], \"narrative.year\": [], \"narrative.lang\": [\"en\", \"fr\"]}",
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      "related_activity_context":"ID: XM-DAC-301-2-110298-003\nTitle: Bacteriocins as an innovative antimicrobial solution for the reduction of antibiotic use in the avian sector. Les bactériocines comme solution antimicrobienne innovante pour la réduction de l’usage des antibiotiques dans le secteur aviaire\nDescription: The poultry industry is one of the most promising economic sectors worldwide, including in low- and moderate-income countries like Tunisia. However, poultry farms are subject to a variety of diseases that can lead to considerable economic losses and major consequences for animal and human health. Further, the overuse of antibiotics has led to a worrying increase in the number of multi-resistant bacteria. In addition, the impact of poultry farms on the environment, food safety and animal protection and welfare issues are now part of consumer demands which need to be considered. \n\nThe first phase of the AviBiocin I project was to assess the potential of bacteriocins (proteins produced by bacteria of one strain and active against those of a closely related strain) as an alternative to antibiotics in the Tunisian poultry industry. This project isolated, characterized and demonstrated the efficacy of certain bacteriocins and assessed their safety, bioavailability and impact. The project also developed eco-responsible technological processes for the pilot production of active bacteriocins. Finally, the prophylactic and therapeutic potential of bacteriocins was demonstrated in experimental poultry houses, through trials in broiler chickens. These trials confirmed the efficacy of bacteriocins under rearing conditions. \n\nIn the second phase of this project, these original, unique and highly promising results will be confirmed on an industrial scale under real poultry farming conditions in Tunisia. It will be funded through InnoVet-AMR 2.0, a four-year partnership between IDRC and the United Kingdom’s Department of Health and Social Care. The initiative is aimed at reducing the emerging risk that anti-microbial resistance in animals poses to global health and food security.\n. L’industrie avicole est l’un des secteurs économiques les plus prometteurs au monde, y compris dans les pays à faible revenu et à revenu intermédiaire comme la Tunisie. Cependant, les élevages de volailles sont confrontés à toute une variété de maladies qui peuvent entraîner des pertes économiques considérables et avoir des conséquences majeures sur la santé animale et humaine. En outre, l’utilisation excessive d’antibiotiques a entraîné une augmentation inquiétante du nombre de bactéries multirésistantes. En outre, les répercussions des élevages de volailles sur l’environnement, la sécurité alimentaire et les questions de protection et de bien-être des animaux font désormais partie des exigences des consommatrices et consommateurs qui doivent être prises en compte. \n\nLa première phase du projet AviBiocin I consistait à évaluer le potentiel des bactériocines (protéines produites par les bactéries d’une souche et actives contre celles d’une souche étroitement apparentée) comme solution de rechange aux antibiotiques dans l’industrie avicole tunisienne. Ce projet a permis d’isoler, de caractériser et de démontrer l’efficacité de certaines bactériocines et d’évaluer leur sécurité, leur biodisponibilité, ainsi que leurs répercussions. Le projet a également permis d’élaborer des procédés technologiques écoresponsables pour la production pilote de bactériocines actives. Enfin, le potentiel prophylactique et thérapeutique des bactériocines a été démontré dans des poulaillers expérimentaux, au moyen d’essais sur des poulets de chair. Ces essais ont confirmé l’efficacité des bactériocines dans le cadre de conditions d’élevage. \n\nDans la deuxième phase de ce projet, ces résultats originaux, uniques et très prometteurs seront confirmés à l’échelle industrielle dans des conditions réelles d’élevage de volailles en Tunisie. Il sera financé dans le cadre de l’initiative Solutions vétérinaires innovatrices pour la résistance aux antimicrobiens 2.0 (InnoVet-AMR 2.0), un partenariat de quatre ans entre le CRDI et le Department of Health and Social Care du Royaume-Uni. Cette initiative vise à réduire les risques émergents que pose la résistance aux antimicrobiens chez les animaux pour la santé mondiale et la sécurité alimentaire.\n \n ID: XM-DAC-301-2-110298-001\nTitle: Bacteriocins as an innovative antimicrobial solution for the reduction of antibiotic use in the avian sector. Les bactériocines comme solution antimicrobienne innovante pour la réduction de l’usage des antibiotiques dans le secteur aviaire\nDescription: The poultry industry is one of the most promising economic sectors worldwide, including in low- and moderate-income countries like Tunisia. However, poultry farms are subject to a variety of diseases that can lead to considerable economic losses and major consequences for animal and human health. Further, the overuse of antibiotics has led to a worrying increase in the number of multi-resistant bacteria. In addition, the impact of poultry farms on the environment, food safety and animal protection and welfare issues are now part of consumer demands which need to be considered. \n\nThe first phase of the AviBiocin I project was to assess the potential of bacteriocins (proteins produced by bacteria of one strain and active against those of a closely related strain) as an alternative to antibiotics in the Tunisian poultry industry. This project isolated, characterized and demonstrated the efficacy of certain bacteriocins and assessed their safety, bioavailability and impact. The project also developed eco-responsible technological processes for the pilot production of active bacteriocins. Finally, the prophylactic and therapeutic potential of bacteriocins was demonstrated in experimental poultry houses, through trials in broiler chickens. These trials confirmed the efficacy of bacteriocins under rearing conditions. \n\nIn the second phase of this project, these original, unique and highly promising results will be confirmed on an industrial scale under real poultry farming conditions in Tunisia. It will be funded through InnoVet-AMR 2.0, a four-year partnership between IDRC and the United Kingdom’s Department of Health and Social Care. The initiative is aimed at reducing the emerging risk that anti-microbial resistance in animals poses to global health and food security.\n. L’industrie avicole est l’un des secteurs économiques les plus prometteurs au monde, y compris dans les pays à faible revenu et à revenu intermédiaire comme la Tunisie. Cependant, les élevages de volailles sont confrontés à toute une variété de maladies qui peuvent entraîner des pertes économiques considérables et avoir des conséquences majeures sur la santé animale et humaine. En outre, l’utilisation excessive d’antibiotiques a entraîné une augmentation inquiétante du nombre de bactéries multirésistantes. En outre, les répercussions des élevages de volailles sur l’environnement, la sécurité alimentaire et les questions de protection et de bien-être des animaux font désormais partie des exigences des consommatrices et consommateurs qui doivent être prises en compte. \n\nLa première phase du projet AviBiocin I consistait à évaluer le potentiel des bactériocines (protéines produites par les bactéries d’une souche et actives contre celles d’une souche étroitement apparentée) comme solution de rechange aux antibiotiques dans l’industrie avicole tunisienne. Ce projet a permis d’isoler, de caractériser et de démontrer l’efficacité de certaines bactériocines et d’évaluer leur sécurité, leur biodisponibilité, ainsi que leurs répercussions. Le projet a également permis d’élaborer des procédés technologiques écoresponsables pour la production pilote de bactériocines actives. Enfin, le potentiel prophylactique et thérapeutique des bactériocines a été démontré dans des poulaillers expérimentaux, au moyen d’essais sur des poulets de chair. Ces essais ont confirmé l’efficacité des bactériocines dans le cadre de conditions d’élevage. \n\nDans la deuxième phase de ce projet, ces résultats originaux, uniques et très prometteurs seront confirmés à l’échelle industrielle dans des conditions réelles d’élevage de volailles en Tunisie. Il sera financé dans le cadre de l’initiative Solutions vétérinaires innovatrices pour la résistance aux antimicrobiens 2.0 (InnoVet-AMR 2.0), un partenariat de quatre ans entre le CRDI et le Department of Health and Social Care du Royaume-Uni. Cette initiative vise à réduire les risques émergents que pose la résistance aux antimicrobiens chez les animaux pour la santé mondiale et la sécurité alimentaire.\n \n ID: XM-DAC-301-2-110298-002\nTitle: Bacteriocins as an innovative antimicrobial solution for the reduction of antibiotic use in the avian sector. Les bactériocines comme solution antimicrobienne innovante pour la réduction de l’usage des antibiotiques dans le secteur aviaire\nDescription: The poultry industry is one of the most promising economic sectors worldwide, including in low- and moderate-income countries like Tunisia. However, poultry farms are subject to a variety of diseases that can lead to considerable economic losses and major consequences for animal and human health. Further, the overuse of antibiotics has led to a worrying increase in the number of multi-resistant bacteria. In addition, the impact of poultry farms on the environment, food safety and animal protection and welfare issues are now part of consumer demands which need to be considered. \n\nThe first phase of the AviBiocin I project was to assess the potential of bacteriocins (proteins produced by bacteria of one strain and active against those of a closely related strain) as an alternative to antibiotics in the Tunisian poultry industry. This project isolated, characterized and demonstrated the efficacy of certain bacteriocins and assessed their safety, bioavailability and impact. The project also developed eco-responsible technological processes for the pilot production of active bacteriocins. Finally, the prophylactic and therapeutic potential of bacteriocins was demonstrated in experimental poultry houses, through trials in broiler chickens. These trials confirmed the efficacy of bacteriocins under rearing conditions. \n\nIn the second phase of this project, these original, unique and highly promising results will be confirmed on an industrial scale under real poultry farming conditions in Tunisia. It will be funded through InnoVet-AMR 2.0, a four-year partnership between IDRC and the United Kingdom’s Department of Health and Social Care. The initiative is aimed at reducing the emerging risk that anti-microbial resistance in animals poses to global health and food security.\n. L’industrie avicole est l’un des secteurs économiques les plus prometteurs au monde, y compris dans les pays à faible revenu et à revenu intermédiaire comme la Tunisie. Cependant, les élevages de volailles sont confrontés à toute une variété de maladies qui peuvent entraîner des pertes économiques considérables et avoir des conséquences majeures sur la santé animale et humaine. En outre, l’utilisation excessive d’antibiotiques a entraîné une augmentation inquiétante du nombre de bactéries multirésistantes. En outre, les répercussions des élevages de volailles sur l’environnement, la sécurité alimentaire et les questions de protection et de bien-être des animaux font désormais partie des exigences des consommatrices et consommateurs qui doivent être prises en compte. \n\nLa première phase du projet AviBiocin I consistait à évaluer le potentiel des bactériocines (protéines produites par les bactéries d’une souche et actives contre celles d’une souche étroitement apparentée) comme solution de rechange aux antibiotiques dans l’industrie avicole tunisienne. Ce projet a permis d’isoler, de caractériser et de démontrer l’efficacité de certaines bactériocines et d’évaluer leur sécurité, leur biodisponibilité, ainsi que leurs répercussions. Le projet a également permis d’élaborer des procédés technologiques écoresponsables pour la production pilote de bactériocines actives. Enfin, le potentiel prophylactique et thérapeutique des bactériocines a été démontré dans des poulaillers expérimentaux, au moyen d’essais sur des poulets de chair. Ces essais ont confirmé l’efficacité des bactériocines dans le cadre de conditions d’élevage. \n\nDans la deuxième phase de ce projet, ces résultats originaux, uniques et très prometteurs seront confirmés à l’échelle industrielle dans des conditions réelles d’élevage de volailles en Tunisie. Il sera financé dans le cadre de l’initiative Solutions vétérinaires innovatrices pour la résistance aux antimicrobiens 2.0 (InnoVet-AMR 2.0), un partenariat de quatre ans entre le CRDI et le Department of Health and Social Care du Royaume-Uni. Cette initiative vise à réduire les risques émergents que pose la résistance aux antimicrobiens chez les animaux pour la santé mondiale et la sécurité alimentaire.\n",
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