{
  "responseHeader":{
    "status":0,
    "QTime":1,
    "params":{
      "q":"recipient_country_code:NG AND reporting_org_ref:GB-GOV-* AND hierarchy:1",
      "fl":"default_lang,default_currency,humanitarian,hierarchy,iati_identifier,reporting_org_ref,reporting_org_type_code,reporting_org_secondary_reporter,reporting_org_narrative,title_narrative,description_narrative,participating_org_ref,participating_org_type,participating_org_role,participating_org_narrative,other_identifier_ref,other_identifier_owner_org_ref,other_identifier_owner_org_narrative,activity_status_code,activity_date_iso_date,activity_date_type,contact_info_organisation_narrative,contact_info_department_narrative,contact_info_person_name_narrative,contact_info_job_title_narrative,contact_info_telephone,contact_info_email,contact_info_website,contact_info_mailing_address_narrative,activity_scope_code,recipient_country_code_position,recipient_country_code,recipient_country_percentage,recipient_region_code,recipient_region_percentage,location_ref,location_id_code,location_id_vocabulary,location_reach_code,location_name_narrative,location_description_narrative,location_activity_description_narrative,location_administrative_vocabulary,location_administrative_code,location_administrative_level,location_point_pos,location_exactness_code,location_class_code,location_feature_designation_code,sector_vocabulary,sector_code,sector_percentage,tag_code,tag_vocabulary,tag_narrative,country_budget_items_vocabulary,country_budget_items_budget_item_code,country_budget_items_budget_item_percentage,country_budget_items_budget_description_narrative,country_budget_items_budget_description_narrative_lang,country_budget_items_budget_description_narrative_text,humanitarian_scope_type,humanitarian_scope_vocabulary,humanitarian_scope_code,humanitarian_scope_narrative,policy_marker_vocabulary,policy_marker_code,policy_marker_significance,collaboration_type_code,default_flow_type_code,default_finance_type_code,default_aid_type_code,default_aid_type_vocabulary,default_tied_status_code,budget_type,budget_status,budget_period_start_iso_date,budget_period_end_iso_date,budget_value_currency,budget_value_currency,budget_value,planned_disbursement_type,planned_disbursement_period_start_iso_date,planned_disbursement_period_end_iso_date,planned_disbursement_value,planned_disbursement_value_date,planned_disbursement_value,planned_disbursement_value_usd,planned_disbursement_provider_org_provider_activity_id,planned_disbursement_provider_org_type,planned_disbursement_provider_org_ref,planned_disbursement_provider_org_narrative,planned_disbursement_provider_org_narrative_lang,planned_disbursement_provider_org_narrative_text,capital_spend_percentage,transaction_ref,transaction_humanitarian,transaction_type,transaction_date_iso_date,transaction_value_currency,transaction_value_date,transaction_value,transaction_value_usd,transaction_provider_org_provider_activity_id,transaction_provider_org_type,transaction_provider_org_ref,transaction_provider_org_narrative,transaction_provider_org_narrative_lang,transaction_provider_org_narrative_text,transaction_disburstment_channel_code,transaction_sector_vocabulary,transaction_sector_vocabulary_uri,transaction_sector_code,transaction_recipient_country_code,transaction_recipient_region_code,transaction_recipient_region_vocabulary,transaction_flow_type_code,transaction_finance_type_code,transaction_aid_type_code,transaction_aid_type_vocabulary,transaction_tied_status_code,document_link_format,document_link_url,document_link_title_narrative,document_link_category_code,document_link_document_date_iso_date,related_activity_ref,related_activity_type,legacy_data_name,legacy_data_value,legacy_data_iati_equivalent,conditions_attached,conditions_condition_type,conditions_condition_narrative,result_type,result_aggregation_status,result_title_narrative,result_description_narrative,result_document_link_*,result_reference_*,result_indicator_*,crs_add_*,fss_*",
      "format":"json"
    }
  },
  "response":{
    "numFound":264,
    "start":0,
    "numFoundExact":true,
    "docs":[{
      "default_currency":"GBP",
      "default_lang":"en",
      "iati_identifier":"GB-GOV-13-FUND--GCRF-MR_S019170_1",
      "reporting_org_ref":"GB-GOV-13",
      "reporting_org_type_code":"10",
      "reporting_org_narrative":["DEPARTMENT FOR BUSINESS, ENERGY & INDUSTRIAL STRATEGY"],
      "title_narrative":["MICA: Development of new agents for the treatment of cryptosporidiosis"],
      "description_narrative":["A recent clinical study in Africa and South Asia has found that cryptosporidiosis is one of the most significant causes of death and illness from diarrheal diseases amongst children in the developing world. Cryptosporidiosis is caused by a single-celled protozoan parasite; the predominant species infecting humans are called Cryptosporidium hominis and Cryptosporidium parvum. This parasite mainly lives in the cells in the gut wall and has a complex life-cycle. Infection occurs due to consumption of water or food contaminated with the parasites. Parasites are spread from an infected individual through their faeces. In people who are healthy and well nourished, the disease clears naturally within a couple of weeks. However, in people who are malnourished (particularly in young children) and people with an immune system that is not functioning properly (for example HIV/AIDS victims), the disease can have a much more significant impact. It is the major contributor to life-threatening diarrhea in young children, with 2.9-4.7 million cases in children under 24 months in sub-Saharan Africa and the Indian sub-continent, leading to more than 200,000 deaths per year. Cryptosporidiosis is also associated with malnutrition and stunted growth in children and probably causes chronic infections, which last for weeks or months. The only drug registered for the treatment of this disease is nitazoxanide, which is not very effective, especially in those patients who are most severely affected due to a weak immune system and/ or malnutrition.   Therefore there is an urgent need for the development of new drugs to treat: (1) children <24 months, especially those that are malnourished and with chronic diarrhea; and (2) immunocompromised children and adults with advanced AIDS and chronic diarrhea. Cryptosporidium may be the cause of as much as 75% of chronic diarrhea in this patient cohort.   We have discovered some chemical starting points that can be used for a drug discovery programme. We have a series of compounds that kill the parasites and also are very effective in clearing the parasites from rodent models of cryptosporidiosis. The compounds are thought to work through preventing the parasite making proteins. The aim of this project is to take these starting points and optimise them to make a molecule which has the potential to be a drug. This will require us to optimise multiple features of the molecule: its ability to kill the parasite, its ability to reach the sites in the body where the parasite resides without being broken down, and its safety. At the end of this project we hope to have a \"preclinical candidate\". This is a compound that we think should be suitable to enter human clinical trials. The steps after this project, prior to human clinical trials will be to make the compound on a larger scale under properly defined conditions and to carry out formal safety testing.","The Global Challenges Research Fund (GCRF) supports cutting-edge research to address challenges faced by developing countries. The fund addresses the UN sustainable development goals. It aims to maximise the impact of research and innovation to improve lives and opportunity in the developing world."],
      "participating_org_ref":["GB-GOV-13","GB-COH-RC000346","GB-COH-RC000346","GB-SC-015096"],
      "participating_org_role":["1","2","3","4"],
      "participating_org_type":["10","15","15","80"],
      "participating_org_narrative":["DEPARTMENT FOR BUSINESS, ENERGY & INDUSTRIAL STRATEGY","MEDICAL RESEARCH COUNCIL","MEDICAL RESEARCH COUNCIL","UNIVERSITY OF DUNDEE"],
      "activity_status_code":"4",
      "activity_date_iso_date":["2018-12-01T00:00:00Z","2019-05-01T00:00:00Z","2021-07-31T00:00:00Z","2023-01-31T00:00:00Z"],
      "activity_date_type":["1","2","3","4"],
      "contact_info_organisation_narrative":["Department of Business Energy and Industrial Strategy"],
      "contact_info_department_narrative":["General enquiries"],
      "contact_info_email":["enquiries@odamanagement.org"],
      "contact_info_website":["https://www.gov.uk/government/publications/beis-official-development-assistance-research-and-innovation"],
      "contact_info_mailing_address_narrative":["Department of Business, Energy and Industrial Strategy, 4th Floor, 1 Victoria Street, SW1H 0ET"],
      "activity_scope_code":"2",
      "recipient_country_code":["BI","KM","ET","KE","MG","MW","MU","MZ","ZW","RW","ER","SO","DJ","SD","SS","TZ","UG","ZM","AO","CM","CF","TD","CG","CD","GA","GQ","ST","ZA","BW","LS","NA","SZ","CV","BJ","GM","GH","GN","GW","CI","LR","ML","MR","NE","NG","SN","SL","SH","TG","BF"],
      "recipient_country_percentage":[2.0408163265306123,2.0408163265306123,2.0408163265306123,2.0408163265306123,2.0408163265306123,2.0408163265306123,2.0408163265306123,2.0408163265306123,2.0408163265306123,2.0408163265306123,2.0408163265306123,2.0408163265306123,2.0408163265306123,2.0408163265306123,2.0408163265306123,2.0408163265306123,2.0408163265306123,2.0408163265306123,2.0408163265306123,2.0408163265306123,2.0408163265306123,2.0408163265306123,2.0408163265306123,2.0408163265306123,2.0408163265306123,2.0408163265306123,2.0408163265306123,2.0408163265306123,2.0408163265306123,2.0408163265306123,2.0408163265306123,2.0408163265306123,2.0408163265306123,2.0408163265306123,2.0408163265306123,2.0408163265306123,2.0408163265306123,2.0408163265306123,2.0408163265306123,2.0408163265306123,2.0408163265306123,2.0408163265306123,2.0408163265306123,2.0408163265306123,2.0408163265306123,2.0408163265306123,2.0408163265306123,2.0408163265306123,2.0408163265306123],
      "sector_code":["12182"],
      "sector_vocabulary":["1"],
      "policy_marker_code":["1","5","6","7","8","10","11","12"],
      "policy_marker_significance":["0","0","0","0","0","0","0","2"],
      "policy_marker_vocabulary":["1","1","1","1","1","1","1","1"],
      "collaboration_type_code":"1",
      "default_flow_type_code":"10",
      "default_finance_type_code":"110",
      "default_aid_type_code":["D02"],
      "default_tied_status_code":"5",
      "budget_status":["1","1"],
      "budget_type":["1","1"],
      "budget_period_start_iso_date":["2019-04-01T00:00:00Z","2020-04-01T00:00:00Z"],
      "budget_period_end_iso_date":["2020-03-31T00:00:00Z","2021-03-31T00:00:00Z"],
      "budget_value":[943848.8,885292.5],
      "budget_value_currency":["GBP","GBP"],
      "capital_spend_percentage":0.0,
      "transaction_type":["3","3","3","3","3","3","3","3","2"],
      "transaction_date_iso_date":["2021-03-31T00:00:00Z","2020-12-31T00:00:00Z","2020-09-30T00:00:00Z","2020-06-30T00:00:00Z","2020-03-31T00:00:00Z","2019-12-31T00:00:00Z","2019-09-30T00:00:00Z","2019-06-30T00:00:00Z","2018-12-01T00:00:00Z"],
      "transaction_value":[179651.53,229893.98,237873.51,237873.53,235962.24,235962.24,235962.24,235962.24,2165959.19],
      "transaction_value_currency":["GBP","GBP","GBP","GBP","GBP","GBP","GBP","GBP"],
      "transaction_value_date":["2021-03-31T00:00:00Z","2020-12-31T00:00:00Z","2020-09-30T00:00:00Z","2020-06-30T00:00:00Z","2020-03-31T00:00:00Z","2019-12-31T00:00:00Z","2019-09-30T00:00:00Z","2019-06-30T00:00:00Z","2018-12-01T00:00:00Z"],
      "hierarchy":1,
      "transaction_value_usd":[248939.80718950738,307480.5939836779,308177.97882575076,297858.9725431336,292014.99550130573,309817.65593052306,291672.5464242103,299125.1818581239,2745736.269544861]
    },{
      "default_currency":"GBP",
      "default_lang":"en",
      "iati_identifier":"GB-GOV-13-FUND--GCRF-MR_T003952_1",
      "reporting_org_ref":"GB-GOV-13",
      "reporting_org_type_code":"10",
      "reporting_org_narrative":["DEPARTMENT FOR BUSINESS, ENERGY & INDUSTRIAL STRATEGY"],
      "title_narrative":["Latent rheumatic heart disease in West Africa: a pilot multi-country study"],
      "description_narrative":["Rheumatic heart disease (RHD) is a disease of poverty affecting the poorest countries in the world, with Sub-Saharan Africa bearing a heavy toll. In 2015, over 33 millions clinical cases and >300,000 deaths worldwide were estimated to be due to RHD. RHD is caused by an excessive immune reaction (\"rheumatic fever\" (ARF)) to throat or skin infections by Group A Streptococcus (GAS) which further damages the heart valves. Complications include heart failure and stroke that result in premature death, usually before 25 years old, and  women with RHD are at higher risk of complication during delivery.  RHD patients with early symptoms can be treated with monthly injections of benzathin penicillin G which stops the evolution of the heart lesions. However, in many countries, including The Gambia, RHD is usually diagnosed in patients attending health facilities at a late stage, with heart failure or other complications, when the efficacy of penicilllin treatment to prevent RHD adverse outcomes is limited. Ideally, penicillin treatment should be started as early as possible although its benefits in individuals with latent RHD, i.e. with cardiac lesions diagnosed by echocardiography but without symptoms, is unknown. Latent RHD represents a potential window of opportunity for early treatment with penicillin to prevent its progression towards overt clinical disease. This intervention needs to be evaluated with a large randomized clinical trial that will recruit hundreds of individuals with latent RHD. Therefore, considering the prevalence of latent RHD is probably 0.5-1% in children (up to 3% in young adults), the study team would need to rapidly screen thousands of individuals to attain the required sample size within a reasonable time period. Handheld echocardiography (HHEC) by non expert users has been proved as a reliable tool to detect RHD and is considered the best option for mass screening. This Trial Development Grant (TDG) will determine i) the prevalence of RHD (latent- and symptomatic) among school-aged children and young adults in peri-urban areas of The Gambia, Senegal and Nigeria; ii) whether non-experts users in the three study sites can be adequately trained for RHD screening using HHEC, and iii) the feasibility and acceptability of community-based screening by HHEC in the three study sites. After HHEC training (3 months), 3,000 children and 3,000 adults per country will be screened and all suspected RHD cases will be confirmed by standard EC before referral to the nearest teaching hospital for adequate management. The feasibility and acceptability of HHEC screenings will be evaluated as an ongoing process through early and regular engagement with participants and all stakeholders involved. Therefore, this TGD will provide useful information on RHD prevalence (both latent and symptomaticin different age groups) and the feasibility and acceptability of mass screening with HHEC, allowing to adapt accordingly the future trial design in the three West African countries. Results of such trial are crucially needed to issue new consensus guidelines on the management of latent RHD and further improve the control of RHD.","The Global Challenges Research Fund (GCRF) supports cutting-edge research to address challenges faced by developing countries. The fund addresses the UN sustainable development goals. It aims to maximise the impact of research and innovation to improve lives and opportunity in the developing world."],
      "participating_org_ref":["GB-GOV-13","GB-COH-RC000346","GB-COH-RC000346"],
      "participating_org_role":["1","2","3","4"],
      "participating_org_type":["10","15","15","80"],
      "participating_org_narrative":["DEPARTMENT FOR BUSINESS, ENERGY & INDUSTRIAL STRATEGY","MEDICAL RESEARCH COUNCIL","MEDICAL RESEARCH COUNCIL","LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE"],
      "activity_status_code":"4",
      "activity_date_iso_date":["2019-10-01T00:00:00Z","2019-10-01T00:00:00Z","2022-03-31T00:00:00Z","2020-12-31T00:00:00Z"],
      "activity_date_type":["1","2","3","4"],
      "contact_info_organisation_narrative":["Department of Business Energy and Industrial Strategy"],
      "contact_info_department_narrative":["General enquiries"],
      "contact_info_email":["enquiries@odamanagement.org"],
      "contact_info_website":["https://www.gov.uk/government/publications/beis-official-development-assistance-research-and-innovation"],
      "contact_info_mailing_address_narrative":["Department of Business, Energy and Industrial Strategy, 4th Floor, 1 Victoria Street, SW1H 0ET"],
      "activity_scope_code":"2",
      "recipient_country_code":["GM","NG","SN"],
      "recipient_country_percentage":[33.333333333333336,33.333333333333336,33.333333333333336],
      "sector_code":["12182"],
      "sector_vocabulary":["1"],
      "policy_marker_code":["1","5","6","7","8","10","11","12"],
      "policy_marker_significance":["0","0","0","0","0","0","0","0"],
      "policy_marker_vocabulary":["1","1","1","1","1","1","1","1"],
      "collaboration_type_code":"1",
      "default_flow_type_code":"10",
      "default_finance_type_code":"110",
      "default_aid_type_code":["D02"],
      "default_tied_status_code":"5",
      "budget_status":["1","1"],
      "budget_type":["1","1"],
      "budget_period_start_iso_date":["2019-04-01T00:00:00Z","2020-04-01T00:00:00Z"],
      "budget_period_end_iso_date":["2020-03-31T00:00:00Z","2021-03-31T00:00:00Z"],
      "budget_value":[73704.18,77687.18],
      "budget_value_currency":["GBP","GBP"],
      "planned_disbursement_type":["1","1"],
      "planned_disbursement_period_start_iso_date":["2021-10-01T00:00:00Z","2022-07-01T00:00:00Z"],
      "planned_disbursement_period_end_iso_date":["2021-12-31T00:00:00Z","2022-09-30T00:00:00Z"],
      "planned_disbursement_value":[5864.43,5864.43],
      "planned_disbursement_provider_org_ref":["GB-GOV-13","GB-GOV-13"],
      "planned_disbursement_provider_org_type":["11","10"],
      "planned_disbursement_provider_org_narrative":["Department for Business, Energy and Industrial Strategy","DEPARTMENT FOR BUSINESS, ENERGY & INDUSTRIAL STRATEGY"],
      "planned_disbursement_provider_org_narrative_text":["Department for Business, Energy and Industrial Strategy","DEPARTMENT FOR BUSINESS, ENERGY & INDUSTRIAL STRATEGY"],
      "planned_disbursement_provider_org_narrative_lang":[" "," "],
      "planned_disbursement_value_date":["2021-10-01T00:00:00Z","2022-07-01T00:00:00Z"],
      "capital_spend_percentage":0.0,
      "transaction_type":["3","3","3","3","2"],
      "transaction_date_iso_date":["2022-09-30T00:00:00Z","2020-09-30T00:00:00Z","2020-06-30T00:00:00Z","2020-03-31T00:00:00Z","2019-10-01T00:00:00Z"],
      "transaction_value":[5864.33,5502.37,7352.72,18426.05,151391.36],
      "transaction_value_currency":["GBP","GBP","GBP","GBP"],
      "transaction_value_date":["2022-09-30T00:00:00Z","2020-09-30T00:00:00Z","2020-06-30T00:00:00Z","2020-03-31T00:00:00Z","2019-10-01T00:00:00Z"],
      "planned_disbursement_value_usd":[8033.652525571468,7027.723992167999],
      "hierarchy":1,
      "transaction_value_usd":[6637.091108370864,7128.617496548674,9206.882432851395,22803.15235122719,191288.0409804799]
    },{
      "default_currency":"GBP",
      "default_lang":"en",
      "iati_identifier":"GB-GOV-13-FUND--GCRF-MR_T021845_1",
      "reporting_org_ref":"GB-GOV-13",
      "reporting_org_type_code":"10",
      "reporting_org_narrative":["DEPARTMENT FOR BUSINESS, ENERGY & INDUSTRIAL STRATEGY"],
      "title_narrative":["Identifying the health systems changes necessary to sustain and scale up the integration of mental health services into primary care in Lagos, Nigeria"],
      "description_narrative":["STATEMENT OF THE PROBLEM:   Despite the huge burden of mental health problems, about 85% of people with severe mental illness in sub-Saharan Africa (SSA) do not receive any form of treatment. Integrating mental health services into primary health care (PHC) has been advocated as the most viable means of closing this treatment gap. The linear model of intervention development, efficacy testing and implementation led to problems with sustainability over time and in real world setting. As there are policy and ethical implications of developing effective heath programmes without sustainability and scale-up, an understanding of the factors and processes that influences sustainability and scale up of an evidence-based intervention is needed for proactive planning   OVERALL AIM: This feasibility study aims to identify the strategies to facilitate the health system changes necessary to sustain and scale up mental health services in primary care in Lagos, Nigeria.  SPECIFIC QUESTIONS TO BE ADRESSED BY THE PROJECT  1) what is the state of implementation of the MeHPriC Project and what are the factors that are currently underlying its implementation?;  2) What are the dynamic interactions between the different components of the programme as regards contexts (inner and outer), implementation processes, implementation actors and intervention outputs and outcomes?;  3) How do these components influence the sustainability of the programme; and  4) What strategies may be required to facilitate the changes necessary for sustainability and scale-up  METHODOLOGY  There are 5 phases of the study.  1. In Phase 1, We will review policy documents and conduct in-depth interviews with selected policy makers to develop hypotheses, assess whether the target indicators for the project are met, identify how they are met, identify the key contextual facilitators and constraints and the way they affect the outcome.  2. In Phase 2, we will conduct a quantitative survey amongst the stakeholders including policy makers and administrators, programme managers, PHC health workers and recipients of care. They will complete scales to assess organisational readiness to change, sustainability and perceived intervention acceptability and feasibility  3. In Phase 3, we will conduct a brief evaluation of the implementation and through in-depth interviews, we will examine the stakeholders' perception about the health systems constraints to delivering, scaling up and sustaining the intervention. We will also observe selected PHC facilities to enable us to understand the factors that act as facilitators or barriers to sustenance of the intervention delivery.  4. In Phase 4, we will conduct a Theory of Change (ToC) workshop that will draw mainly on the results from the analysis of the earlier phases in combination with scientific knowledge and programme experience to identify health system changes that will improve sustainability in the delivery of the intervention. 5. In Phase 5, we will analysis and present the project report to the funders and the stakeholders   RESEARCH IMPACT: 1. The individual care recipients will benefit from sustained level of evidence-based interventions leading to better outcomes and improved quality of life.  2. This study will enhance the health workers knowledge, motivation and attitude in providing effective mental health interventions in a sustainable way.  3. The programme implementers will be able to identify and include sustainability components to their design and implementation of complex interventions.  4. Evidence generated in this study will be shared with the WHO team to inform potential strategies for a sustainability and scalability of mental health interventions in LMICs.  5. The project will inform Policy makers on methods of sustaining beneficial interventions thereby maximizing the judicious use of funds","The Global Challenges Research Fund (GCRF) supports cutting-edge research to address challenges faced by developing countries. The fund addresses the UN sustainable development goals. It aims to maximise the impact of research and innovation to improve lives and opportunity in the developing world."],
      "participating_org_ref":["GB-GOV-13","GB-COH-RC000346","GB-COH-RC000346"],
      "participating_org_role":["1","2","3","4"],
      "participating_org_type":["10","15","15","80"],
      "participating_org_narrative":["DEPARTMENT FOR BUSINESS, ENERGY & INDUSTRIAL STRATEGY","MEDICAL RESEARCH COUNCIL","MEDICAL RESEARCH COUNCIL","LAGOS STATE UNIVERSITY COLLEGE OF MEDICINE"],
      "activity_status_code":"4",
      "activity_date_iso_date":["2019-12-02T00:00:00Z","2020-09-01T00:00:00Z","2021-11-01T00:00:00Z","2021-03-31T00:00:00Z"],
      "activity_date_type":["1","2","3","4"],
      "contact_info_organisation_narrative":["Department of Business Energy and Industrial Strategy"],
      "contact_info_department_narrative":["General enquiries"],
      "contact_info_email":["enquiries@odamanagement.org"],
      "contact_info_website":["https://www.gov.uk/government/publications/beis-official-development-assistance-research-and-innovation"],
      "contact_info_mailing_address_narrative":["Department of Business, Energy and Industrial Strategy, 4th Floor, 1 Victoria Street, SW1H 0ET"],
      "activity_scope_code":"4",
      "recipient_country_code":["NG"],
      "recipient_country_percentage":[100.0],
      "sector_code":["12182"],
      "sector_vocabulary":["1"],
      "policy_marker_code":["1","5","6","7","8","10","11","12"],
      "policy_marker_significance":["0","0","0","0","0","0","2","0"],
      "policy_marker_vocabulary":["1","1","1","1","1","1","1","1"],
      "collaboration_type_code":"1",
      "default_flow_type_code":"10",
      "default_finance_type_code":"110",
      "default_aid_type_code":["D02"],
      "default_tied_status_code":"5",
      "budget_status":["1"],
      "budget_type":["1"],
      "budget_period_start_iso_date":["2020-04-01T00:00:00Z"],
      "budget_period_end_iso_date":["2021-03-31T00:00:00Z"],
      "budget_value":[57902.92],
      "budget_value_currency":["GBP"],
      "capital_spend_percentage":0.0,
      "transaction_type":["3","3","2"],
      "transaction_date_iso_date":["2021-03-31T00:00:00Z","2020-12-31T00:00:00Z","2019-12-02T00:00:00Z"],
      "transaction_value":[28951.46,28951.46,194706.16],
      "transaction_value_currency":["GBP","GBP"],
      "transaction_value_date":["2021-03-31T00:00:00Z","2020-12-31T00:00:00Z","2019-12-02T00:00:00Z"],
      "hierarchy":1,
      "transaction_value_usd":[40117.503425964336,38722.24978442102,255648.55667768442]
    },{
      "default_currency":"GBP",
      "default_lang":"en",
      "iati_identifier":"GB-GOV-13-FUND--GCRF-MR_T005092_1",
      "reporting_org_ref":"GB-GOV-13",
      "reporting_org_type_code":"10",
      "reporting_org_narrative":["DEPARTMENT FOR BUSINESS, ENERGY & INDUSTRIAL STRATEGY"],
      "title_narrative":["A feasibility and pilot trial of enteral probiotic administration in preterm infants admitted to a neonatal unit in Nigeria"],
      "description_narrative":["Globally in 2017, amongst the 5.4 million children who died under the age of 5 years, almost 1 in 2 of these deaths (46%) occurred in the first month of life. Worldwide, 20 million newborns (up to 1 in 5 of all births) are low birth weight (LBW; weighing <2,500g) resulting from prematurity (being born too early) and/or poor growth in the womb. 80% of neonatal deaths occur in these small infants and long-term impairments are common amongst survivors. The greatest burden of preterm births and newborn deaths occur in low and middle-income countries and over one third of newborn deaths occur in sub-Saharan Africa (sSA). These high rates of death, and disability, including long-term impaired learning, amongst preterm and low birthweight (LBW) infants present a major challenge to families and health services in low and middle-income countries.   The most vulnerable newborns are nursed in neonatal units which are able to provide only a limited range of interventions. We have established a network of 7 neonatal units in Nigeria and Kenya. Each of these units typically admit between several hundreds to over one thousand babies each year. They are able to support feeding (e.g. using naso-gastric tubes), treat infections and also practice Kangaroo Mother Care where once babies are stable they are placed skin-to-skin usually with their mothers. More advanced levels of care are not available and access to laboratory investigations and Xrays is limited.  About 1 in 4 (25%) of babies born before 36 weeks of pregnancy and admitted to these units die. Major causes of death are complications of prematurity and infections. In addition, advanced methods of feeding, such as feeding through the veins, are not available, and establishing and progressing feeds safely in small babies is difficult. This is important because babies who are feeding well can usually be discharged from the unit which reduces their risk of infection and reduces healthcare costs and the workload for staff.  We propose to evaluate whether giving a daily oral supplement of probiotics (live bacteria that have health benefits) would benefit these vulnerable babies. Probiotics have been given to many thousands of highly vulnerable preterm infants in research studies done in high-income countries and some poorer countries but they have not been adequately tested in sub-Saharan Africa. There is convincing evidence form this research that probiotics reduce deaths from all causes, prevent infections and also speed-up tolerance of oral feeds without causing harmful effects.   Before we can design large research study of probiotics for preterm babies in neonatal units in sub-Saharan Africa, we need to do some preparatory work. In this study, we plan to test the feasibility and likely effectiveness of giving a probiotic in one large neonatal unit in Ibadan, Nigeria. We will also develop the necessary process for undertaking high-quality research even in a low-resource setting. This initial study will be done over 22 months. We plan to invite the parents of 100 babies born before 36 weeks of pregnancy to join the study. The babies would be allocated randomly to receive either the daily probiotic or a matched placebo (inactive preparation) during their stay on the unit. We would monitor the babies closely and record important events such as episodes of infection diagnosed using optimal laboratory procedures provided through the trial.  The main question to be addressed by this initial study is whether it is possible to undertake a much larger study in this setting to reliably assess the potential benefits of probiotics for these highly vulnerable babies.","The Global Challenges Research Fund (GCRF) supports cutting-edge research to address challenges faced by developing countries. The fund addresses the UN sustainable development goals. It aims to maximise the impact of research and innovation to improve lives and opportunity in the developing world."],
      "participating_org_ref":["GB-GOV-13","GB-COH-RC000346","GB-COH-RC000346"],
      "participating_org_role":["1","2","3"],
      "participating_org_type":["10","15","15"],
      "participating_org_narrative":["DEPARTMENT FOR BUSINESS, ENERGY & INDUSTRIAL STRATEGY","MEDICAL RESEARCH COUNCIL","MEDICAL RESEARCH COUNCIL"],
      "activity_status_code":"4",
      "activity_date_iso_date":["2019-06-03T00:00:00Z","2019-12-01T00:00:00Z","2021-06-02T00:00:00Z","2021-03-31T00:00:00Z"],
      "activity_date_type":["1","2","3","4"],
      "contact_info_organisation_narrative":["Department of Business Energy and Industrial Strategy"],
      "contact_info_department_narrative":["General enquiries"],
      "contact_info_email":["enquiries@odamanagement.org"],
      "contact_info_website":["https://www.gov.uk/government/publications/beis-official-development-assistance-research-and-innovation"],
      "contact_info_mailing_address_narrative":["Department of Business, Energy and Industrial Strategy, 4th Floor, 1 Victoria Street, SW1H 0ET"],
      "activity_scope_code":"2",
      "recipient_country_code":["KE","NG"],
      "recipient_country_percentage":[50.0,50.0],
      "sector_code":["12182"],
      "sector_vocabulary":["1"],
      "policy_marker_code":["1","5","6","7","8","10","11","12"],
      "policy_marker_significance":["0","0","0","0","0","0","0","0"],
      "policy_marker_vocabulary":["1","1","1","1","1","1","1","1"],
      "collaboration_type_code":"1",
      "default_flow_type_code":"10",
      "default_finance_type_code":"110",
      "default_aid_type_code":["D02"],
      "default_tied_status_code":"5",
      "budget_status":["1","1"],
      "budget_type":["1","1"],
      "budget_period_start_iso_date":["2019-04-01T00:00:00Z","2020-04-01T00:00:00Z"],
      "budget_period_end_iso_date":["2020-03-31T00:00:00Z","2021-03-31T00:00:00Z"],
      "budget_value":[5039.52,5195.33],
      "budget_value_currency":["GBP","GBP"],
      "capital_spend_percentage":0.0,
      "transaction_type":["3","3","2"],
      "transaction_date_iso_date":["2020-06-30T00:00:00Z","2020-03-31T00:00:00Z","2019-06-03T00:00:00Z"],
      "transaction_value":[5195.33,5039.52,166041.62],
      "transaction_value_currency":["GBP","GBP"],
      "transaction_value_date":["2020-06-30T00:00:00Z","2020-03-31T00:00:00Z","2019-06-03T00:00:00Z"],
      "hierarchy":1,
      "transaction_value_usd":[6505.4554654421545,6236.656382515865,210488.0415549433]
    },{
      "default_currency":"GBP",
      "default_lang":"en",
      "iati_identifier":"GB-GOV-13-FUND--GCRF-MR_M01472X_1",
      "reporting_org_ref":"GB-GOV-13",
      "reporting_org_type_code":"10",
      "reporting_org_narrative":["DEPARTMENT FOR BUSINESS, ENERGY & INDUSTRIAL STRATEGY"],
      "title_narrative":["Determinants of effectiveness of a novel community health workers programme in improving maternal and child health in Nigeria"],
      "description_narrative":["Improved mother and child health (MCH) continues to be an issue of international priority, particularly for sub-Saharan African countries. Evidence suggests that schemes involving Community Health Worker (CHWs) can be effective in improving the health of mothers and children. Although such schemes are implemented in some developing countries such as Bangladesh, to guide further developments, much better understanding is needed on what makes CHW programmes successful and under what circumstances.   In Nigeria, despite significant improvements, mother and child health remains an issue of concern, particularly in rural areas where most vulnerable groups live. In 2012, the Federal Government of Nigeria established the Subsidy Reinvestment and Empowerment Programme (SURE-P) to invest the revenue from fuel subsidy reduction into a social security programme to improve lives of most vulnerable populations.   One SURE-P component, implemented in selected facilities in each State, focuses on maternal and child health (SURE-P/MCH). The idea is that recruitment of CHWs, combined with infrastructure development, and improved availability of supplies and medicines, will improve access to quality health services, and ultimately, improve mother and child health. Since December 2012, Conditional Cash Transfers (CCT) have also been added at selected sites ('SURE-P/MCH+CCT'). These incentive payments to pregnant mothers are linked to use of health services at different stages: e.g. for antenatal care visits and facility deliveries.   The AIM of this project is to inform strengthening and scaling up of community health worker (CHW) programmes. This will be achieved by investigating two implementations (i.e. with and without conditional cash transfers) of a Nigerian CHW programme, to understand what factors, under what conditions, promote equitable access to quality services, and improve maternal and child health outcomes. We will do so by: 1.Developing an in-depth understanding of the context and the process of implementation of the interventions, including relations between health workforce and infrastructure and supplies; 2.Identifying, assessing and comparing the intervention outputs (e.g. skills and practices of CHWs and efficiency of primary health care facilities) and outcomes (e.g. equitable access to quality MCH services and attainment of MCH outcome targets); 3.Developing an empirically-based and theoretically-grounded model of complex relations between the people involved, context, implementation process, outputs and outcomes of the interventions; 4.Developing transferable best practices for scalability (expansion within a broadly similar context) and generalizability (expansion to different contexts) of the interventions.  This five-year research and development project will be implemented in two States in Nigeria - Niger State in the North and Anambra State in the South, which were selected in consultation with the Federal MOH and SURE-P national programme officer. Selecting two states from different parts of the country will provide an opportunity for different contextual factors that affect the implementation and outcome from the programme to be better elucidated and ensure that the findings are generalisable to the entire country. Within each State we will select three Local Government Areas (LGAs) clusters: one with SURE-P/MCH, one with SURE-P/MCH+CCT and one with no intervention. In each State the two interventions will be assessed against each other and against the comparison (i.e. no implementation) site.   We will work closely with local, State and Federal policymakers and practitioners, to generate answers that can be used to inform their policy decisions. We expect that better understanding of performance of the CHW programme in Nigeria will inform further strengthening of the existing programme, its replication within Nigeria, and other similar countries considering the implementation of CHW initiatives.","The Global Challenges Research Fund (GCRF) supports cutting-edge research to address challenges faced by developing countries. The fund addresses the UN sustainable development goals. It aims to maximise the impact of research and innovation to improve lives and opportunity in the developing world."],
      "participating_org_ref":["GB-GOV-13","GB-COH-RC000346","GB-COH-RC000346"],
      "participating_org_role":["1","2","3"],
      "participating_org_type":["10","15","15"],
      "participating_org_narrative":["DEPARTMENT FOR BUSINESS, ENERGY & INDUSTRIAL STRATEGY","MEDICAL RESEARCH COUNCIL","MEDICAL RESEARCH COUNCIL"],
      "activity_status_code":"4",
      "activity_date_iso_date":["2015-01-01T00:00:00Z","2015-06-01T00:00:00Z","2019-12-31T00:00:00Z","2021-02-28T00:00:00Z"],
      "activity_date_type":["1","2","3","4"],
      "contact_info_organisation_narrative":["Department of Business Energy and Industrial Strategy"],
      "contact_info_department_narrative":["General enquiries"],
      "contact_info_email":["enquiries@odamanagement.org"],
      "contact_info_website":["https://www.gov.uk/government/publications/beis-official-development-assistance-research-and-innovation"],
      "contact_info_mailing_address_narrative":["Department of Business, Energy and Industrial Strategy, 4th Floor, 1 Victoria Street, SW1H 0ET"],
      "activity_scope_code":"4",
      "recipient_country_code":["NG"],
      "recipient_country_percentage":[100.0],
      "sector_code":["12182"],
      "sector_vocabulary":["1"],
      "policy_marker_code":["1","5","6","7","8","10","11","12"],
      "policy_marker_significance":["2","0","0","0","0","0","0","0"],
      "policy_marker_vocabulary":["1","1","1","1","1","1","1","1"],
      "collaboration_type_code":"1",
      "default_flow_type_code":"10",
      "default_finance_type_code":"110",
      "default_aid_type_code":["D02"],
      "default_tied_status_code":"5",
      "budget_status":["1","1","1","1","1"],
      "budget_type":["1","1","1","1","1"],
      "budget_period_start_iso_date":["2015-04-01T00:00:00Z","2016-04-01T00:00:00Z","2017-04-01T00:00:00Z","2018-04-01T00:00:00Z","2019-04-01T00:00:00Z"],
      "budget_period_end_iso_date":["2016-03-31T00:00:00Z","2017-03-31T00:00:00Z","2018-03-31T00:00:00Z","2019-03-31T00:00:00Z","2020-03-31T00:00:00Z"],
      "budget_value":[117452.1,157490.68,79191.68,159882.36,161092.78],
      "budget_value_currency":["GBP","GBP","GBP","GBP","GBP"],
      "planned_disbursement_type":["1"],
      "planned_disbursement_period_start_iso_date":["2021-10-01T00:00:00Z"],
      "planned_disbursement_period_end_iso_date":["2021-12-31T00:00:00Z"],
      "planned_disbursement_value":[39946.27],
      "planned_disbursement_provider_org_ref":["GB-GOV-13"],
      "planned_disbursement_provider_org_type":["11"],
      "planned_disbursement_provider_org_narrative":["Department for Business, Energy and Industrial Strategy"],
      "planned_disbursement_provider_org_narrative_text":["Department for Business, Energy and Industrial Strategy"],
      "planned_disbursement_provider_org_narrative_lang":[" "],
      "planned_disbursement_value_date":["2021-10-01T00:00:00Z"],
      "capital_spend_percentage":0.0,
      "transaction_type":["3","3","3","3","3","3","3","3","3","3","3","3","3","3","3","2"],
      "transaction_date_iso_date":["2021-12-31T00:00:00Z","2020-03-31T00:00:00Z","2019-12-31T00:00:00Z","2019-09-30T00:00:00Z","2019-06-30T00:00:00Z","2019-03-31T00:00:00Z","2018-12-31T00:00:00Z","2018-09-30T00:00:00Z","2018-06-30T00:00:00Z","2018-03-31T00:00:00Z","2017-06-30T00:00:00Z","2017-03-31T00:00:00Z","2016-12-31T00:00:00Z","2016-09-30T00:00:00Z","2016-06-30T00:00:00Z","2015-01-01T00:00:00Z"],
      "transaction_value":[39139.53,13449.67,13449.67,13449.67,13348.6,13348.6,13348.6,13348.6,13248.33,13248.33,13148.88,13148.88,13148.88,13148.88,13050.23,794948.39],
      "transaction_value_currency":["GBP","GBP","GBP","GBP","GBP","GBP","GBP","GBP","GBP","GBP","GBP","GBP","GBP","GBP","GBP"],
      "transaction_value_date":["2021-12-31T00:00:00Z","2020-03-31T00:00:00Z","2019-12-31T00:00:00Z","2019-09-30T00:00:00Z","2019-06-30T00:00:00Z","2019-03-31T00:00:00Z","2018-12-31T00:00:00Z","2018-09-30T00:00:00Z","2018-06-30T00:00:00Z","2018-03-31T00:00:00Z","2017-06-30T00:00:00Z","2017-03-31T00:00:00Z","2016-12-31T00:00:00Z","2016-09-30T00:00:00Z","2016-06-30T00:00:00Z","2015-01-01T00:00:00Z"],
      "planned_disbursement_value_usd":[54722.190029151985],
      "hierarchy":1,
      "transaction_value_usd":[51948.722541725576,16644.634855746608,17659.373094776005,16625.115516216956,16921.78546258653,17580.17364176321,16921.71086919072,17435.459738373946,17608.79427648246,18508.024403785334,16832.762920771107,16217.05495899348,16431.004341974574,17278.126164152756,18547.657707655537,1203283.1151632317]
    },{
      "default_currency":"GBP",
      "default_lang":"en",
      "iati_identifier":"GB-GOV-13-FUND--GCRF-MR_T039140_1",
      "reporting_org_ref":"GB-GOV-13",
      "reporting_org_type_code":"10",
      "reporting_org_narrative":["DEPARTMENT FOR BUSINESS, ENERGY & INDUSTRIAL STRATEGY"],
      "title_narrative":["Challenges and opportunities of providing evidence based perinatal psychological care for couples with stillbirth (SB) in Lagos Nigeria"],
      "description_narrative":["Sub-Saharan Africa faces the highest burden of stillbirths with Nigeria contributing around 12% of global burden of stillbirth (with about 314,000 stillbirths/year) and an estimated stillbirth rate of 42.9 per 1000 births . Stillbirth is associated with substantial psychological, social, economic and intangible cost to women, their families, healthcare providers and the wider society . Stillbirth in SSA countries brings many challenges to the mother including poor health, grief, sadness, and coping with community perceptions. The mothers' grief experiences following stillbirth are further complicated by the biological fact of death occurring within the body; generating feelings of anxiety, failure, and guilt. Studies have shown that guild and shame plays a very important role in predicting the intensity of later grief . The father is not left out of these difficulties. High rates of depression, anxiety, post-traumatic stress disorders and marital breakup has been observed in couples with stillbirth.  For many couples in SSA, it takes a long time to recover from stillbirth, and in many instances only when another baby is born and survives, some few other never recovers. In Nigeria and many parts of SSA, the couple's grief is further compounded by many of the communities deeply rooted cultural practices and beliefs.   Many Africa communities attribute stillbirth to spirits or supernatural powers, so bereaved parents avoid public burials and displays of grief, fearing such action could evoke future malice or lead to infertility. In many Africa traditions, women with stillbirth are accused of induced abortion and couples with stillbirth are forbidden from mourning and those who repeatedly lose their babies are blamed, mistreated, and dishonored. These harsh traditional value judgments about stillbirth in most African communities' results in high level of stigma and pushes many couples to keep stillbirths a secret. Problem with health systems:   Apart from the stigma from the community, mothers who experience stillbirths are often overlooked midwives and other perinatal health workers who tend to focus on maternal and child health. Many health workers are ill equipped to handle grief that comes with stillbirth. Also, studies have shown that many healthcare providers may be avoidant, feel helpless and guilty or they may experience a sense of failure when the baby dies.  Many health workers are not equipped to handle perinatal bereavement care. Also most of the guidelines of care after stillbirth reflect the western sociocultural perspectives and may not be appropriate in the African setting in view of the socio-cultural norms and nuances regarding stillbirth.   In order to design a n effective, sociocultural acceptable intervention package of care and support for couples with stillbirth in Nigeria, it is necessary to first have a detail understanding of the peculiar sociocultural issues regarding stillbirth in the community, the specific psychological and social impacts of stillbirth that needs to be prevented, the preferences and perception of the affected couple to perinatal bereavement care and the health systems challenges and opportunities for delivering the intervention. Outcome expected as immediate result of the proposal:   TThe results of this proposal will provide a deeper understanding of social perceptions of stillbirth in Nigeria and other SSA countries which is a crucial step towards reducing the isolation, grief, and stigma attached to stillbirth. It will also provide insight into the psycho-social burden of stillbirth, enumerate the challenges and opportunities for providing socio-culturally relevant bereavement care to coupes with stillbirth and most importantly lead to the development and feasibility assessment of an intervention package for support and care for Nigerian women with stillbirth","The Global Challenges Research Fund (GCRF) supports cutting-edge research to address challenges faced by developing countries. The fund addresses the UN sustainable development goals. It aims to maximise the impact of research and innovation to improve lives and opportunity in the developing world."],
      "participating_org_ref":["GB-GOV-13","GB-COH-RC000346","GB-COH-RC000346"],
      "participating_org_role":["1","2","3"],
      "participating_org_type":["10","15","15"],
      "participating_org_narrative":["DEPARTMENT FOR BUSINESS, ENERGY & INDUSTRIAL STRATEGY","MEDICAL RESEARCH COUNCIL","MEDICAL RESEARCH COUNCIL"],
      "activity_status_code":"4",
      "activity_date_iso_date":["2020-06-01T00:00:00Z","2020-09-01T00:00:00Z","2021-10-31T00:00:00Z","2021-10-31T00:00:00Z"],
      "activity_date_type":["1","2","3","4"],
      "contact_info_organisation_narrative":["Department of Business Energy and Industrial Strategy"],
      "contact_info_department_narrative":["General enquiries"],
      "contact_info_email":["enquiries@odamanagement.org"],
      "contact_info_website":["https://www.gov.uk/government/publications/beis-official-development-assistance-research-and-innovation"],
      "contact_info_mailing_address_narrative":["Department of Business, Energy and Industrial Strategy, 4th Floor, 1 Victoria Street, SW1H 0ET"],
      "activity_scope_code":"4",
      "recipient_country_code":["NG"],
      "recipient_country_percentage":[100.0],
      "sector_code":["12182"],
      "sector_vocabulary":["1"],
      "policy_marker_code":["1","5","6","7","8","10","11","12"],
      "policy_marker_significance":["0","0","0","0","0","0","0","0"],
      "policy_marker_vocabulary":["1","1","1","1","1","1","1","1"],
      "collaboration_type_code":"1",
      "default_flow_type_code":"10",
      "default_finance_type_code":"110",
      "default_aid_type_code":["D02"],
      "default_tied_status_code":"5",
      "budget_status":["1","1"],
      "budget_type":["1","1"],
      "budget_period_start_iso_date":["2020-04-01T00:00:00Z","2021-04-01T00:00:00Z"],
      "budget_period_end_iso_date":["2021-03-31T00:00:00Z","2022-03-31T00:00:00Z"],
      "budget_value":[59830.74,38660.64],
      "budget_value_currency":["GBP","GBP"],
      "planned_disbursement_type":["2"],
      "planned_disbursement_period_start_iso_date":["2022-04-01T00:00:00Z"],
      "planned_disbursement_period_end_iso_date":["2022-06-30T00:00:00Z"],
      "planned_disbursement_value":[-4754.1],
      "planned_disbursement_provider_org_ref":["GB-GOV-13"],
      "planned_disbursement_provider_org_type":["11"],
      "planned_disbursement_provider_org_narrative":["DEPARTMENT FOR BUSINESS, ENERGY AND INDUSTRIAL STRATEGY"],
      "planned_disbursement_provider_org_narrative_text":["DEPARTMENT FOR BUSINESS, ENERGY AND INDUSTRIAL STRATEGY"],
      "planned_disbursement_provider_org_narrative_lang":[" "],
      "planned_disbursement_value_date":["2022-04-01T00:00:00Z"],
      "capital_spend_percentage":0.0,
      "transaction_type":["3","3","3","2"],
      "transaction_date_iso_date":["2022-06-30T00:00:00Z","2021-03-31T00:00:00Z","2020-12-31T00:00:00Z","2020-06-01T00:00:00Z"],
      "transaction_value":[-3525.06,9665.16,20250.21,98491.38],
      "transaction_value_currency":["GBP","GBP","GBP"],
      "transaction_value_date":["2022-06-30T00:00:00Z","2021-03-31T00:00:00Z","2020-12-31T00:00:00Z","2020-06-01T00:00:00Z"],
      "planned_disbursement_value_usd":[-6151.940438726945],
      "hierarchy":1,
      "transaction_value_usd":[-4340.184956856737,13392.833708990618,27084.42647821493,123328.31337372989]
    },{
      "default_currency":"GBP",
      "default_lang":"en",
      "iati_identifier":"GB-GOV-13-FUND--GCRF-MR_V030817_1",
      "reporting_org_ref":"GB-GOV-13",
      "reporting_org_type_code":"10",
      "reporting_org_narrative":["DEPARTMENT FOR BUSINESS, ENERGY & INDUSTRIAL STRATEGY"],
      "title_narrative":["Development and pilot testing of an m-health intervention to reduce COVID-19 associated psychosocial distress among Nigerian healthcare workers"],
      "description_narrative":["MRC GECO COVID award to develop and pilot test an m-health intervention to reduce COVID-19 associated psychosocial distress among Nigerian healthcare workers COVID-19","The Global Challenges Research Fund (GCRF) supports cutting-edge research to address challenges faced by developing countries. The fund addresses the UN sustainable development goals. It aims to maximise the impact of research and innovation to improve lives and opportunity in the developing world."],
      "participating_org_ref":["GB-GOV-13","GB-COH-RC000346","GB-COH-RC000346"],
      "participating_org_role":["1","2","3"],
      "participating_org_type":["10","15","15"],
      "participating_org_narrative":["DEPARTMENT FOR BUSINESS, ENERGY & INDUSTRIAL STRATEGY","MEDICAL RESEARCH COUNCIL","MEDICAL RESEARCH COUNCIL"],
      "activity_status_code":"3",
      "activity_date_iso_date":["2020-09-14T00:00:00Z","2020-10-28T00:00:00Z","2022-03-31T00:00:00Z","2022-03-31T00:00:00Z"],
      "activity_date_type":["1","2","3","4"],
      "contact_info_organisation_narrative":["Department of Business Energy and Industrial Strategy"],
      "contact_info_department_narrative":["General enquiries"],
      "contact_info_email":["enquiries@odamanagement.org"],
      "contact_info_website":["https://www.gov.uk/government/publications/beis-official-development-assistance-research-and-innovation"],
      "contact_info_mailing_address_narrative":["Department of Business, Energy and Industrial Strategy, 4th Floor, 1 Victoria Street, SW1H 0ET"],
      "activity_scope_code":"4",
      "recipient_country_code":["NG"],
      "recipient_country_percentage":[100.0],
      "sector_code":["12264"],
      "sector_vocabulary":["1"],
      "policy_marker_code":["1","5","6","7","8","10","11","12"],
      "policy_marker_significance":["0","0","0","0","0","0","2","0"],
      "policy_marker_vocabulary":["1","1","1","1","1","1","1","1"],
      "collaboration_type_code":"1",
      "default_flow_type_code":"10",
      "default_finance_type_code":"110",
      "default_aid_type_code":["D02"],
      "default_tied_status_code":"5",
      "budget_status":["1","1"],
      "budget_type":["1","1"],
      "budget_period_start_iso_date":["2020-04-01T00:00:00Z","2021-04-01T00:00:00Z"],
      "budget_period_end_iso_date":["2021-03-31T00:00:00Z","2022-03-31T00:00:00Z"],
      "budget_value":[69388.02,96641.59],
      "budget_value_currency":["GBP","GBP"],
      "planned_disbursement_type":["2","2","1","1","1"],
      "planned_disbursement_period_start_iso_date":["2022-01-01T00:00:00Z","2022-07-01T00:00:00Z","2022-10-01T00:00:00Z","2023-01-01T00:00:00Z","2023-04-01T00:00:00Z"],
      "planned_disbursement_period_end_iso_date":["2022-03-31T00:00:00Z","2022-09-30T00:00:00Z","2022-12-31T00:00:00Z","2023-03-31T00:00:00Z","2023-06-30T00:00:00Z"],
      "planned_disbursement_value":[7412.95,16025.21,25944.26,25944.0,25944.26],
      "planned_disbursement_provider_org_ref":["GB-GOV-13","GB-GOV-13","GB-GOV-13","GB-GOV-13","GB-GOV-13"],
      "planned_disbursement_provider_org_type":["11","10","10","10","10"],
      "planned_disbursement_provider_org_narrative":["Department for Business, Energy and Industrial Strategy","DEPARTMENT FOR BUSINESS, ENERGY & INDUSTRIAL STRATEGY","DEPARTMENT FOR BUSINESS, ENERGY & INDUSTRIAL STRATEGY","DEPARTMENT FOR BUSINESS, ENERGY & INDUSTRIAL STRATEGY","DEPARTMENT FOR BUSINESS, ENERGY & INDUSTRIAL STRATEGY"],
      "planned_disbursement_provider_org_narrative_text":["Department for Business, Energy and Industrial Strategy","DEPARTMENT FOR BUSINESS, ENERGY & INDUSTRIAL STRATEGY","DEPARTMENT FOR BUSINESS, ENERGY & INDUSTRIAL STRATEGY","DEPARTMENT FOR BUSINESS, ENERGY & INDUSTRIAL STRATEGY","DEPARTMENT FOR BUSINESS, ENERGY & INDUSTRIAL STRATEGY"],
      "planned_disbursement_provider_org_narrative_lang":[" "," "," "," "," "],
      "planned_disbursement_value_date":["2022-01-01T00:00:00Z","2022-07-01T00:00:00Z","2022-10-01T00:00:00Z","2023-01-01T00:00:00Z","2023-04-01T00:00:00Z"],
      "capital_spend_percentage":0.0,
      "transaction_type":["3","3","3","3","3","2"],
      "transaction_date_iso_date":["2023-09-30T00:00:00Z","2021-09-30T00:00:00Z","2021-06-30T00:00:00Z","2021-03-31T00:00:00Z","2020-12-31T00:00:00Z","2020-09-14T00:00:00Z"],
      "transaction_value":[-26659.05,1976.2,4293.41,16137.29,18556.73,166029.61],
      "transaction_value_currency":["GBP","GBP","GBP","GBP","GBP"],
      "transaction_value_date":["2023-09-30T00:00:00Z","2021-09-30T00:00:00Z","2021-06-30T00:00:00Z","2021-03-31T00:00:00Z","2020-12-31T00:00:00Z","2020-09-14T00:00:00Z"],
      "planned_disbursement_value_usd":[10042.639350962803,19204.040767223847,29302.47031845887,31702.089282376248,32296.25872330329],
      "hierarchy":1,
      "transaction_value_usd":[-33799.68904639227,2712.349816133144,6023.500777090134,22361.144718117157,24819.41616215759,215100.32636684785]
    },{
      "default_currency":"GBP",
      "default_lang":"en",
      "iati_identifier":"GB-GOV-13-FUND--GCRF-MR_N029984_1",
      "reporting_org_ref":"GB-GOV-13",
      "reporting_org_type_code":"10",
      "reporting_org_narrative":["DEPARTMENT FOR BUSINESS, ENERGY & INDUSTRIAL STRATEGY"],
      "title_narrative":["Development grant for a multicentre, randomised trial to reduce surgical site infection following emergency gastrointestinal surgery in LMICs"],
      "description_narrative":["THE PROBLEM: Infections in wounds after bowel surgery are common in all countries. They have adverse effects for patients, doctors and health systems. For patients, they are painful, smelly, reduce quality of life and reduce time taken to return to normal activities. They are hard to treat and require prescriptions of long courses of antibiotics and return trips to the operating theatre, increasing antibiotic resistance and reducing future available treatments. They are extremely costly and require long lengths of stay in hospital and lots of nursing time. In low and middle-income countries, they are at least twice as common as they are in high-income countries. Rates of antibiotic resistance are also higher, meaning they are even harder to treat. Wound infections affect both adults and children and since people of working age can't return quickly to work, their families and communities are also adversely affected.  FUTURE PROPOSED TRIAL: We aim to perform a large, multi-country randomised controlled trial looking at two simple interventions to reduce wound infections after emergency bowel surgery. Emergency surgery is the most common, demanding and burdensome type of bowel surgery in low and middle income countries (LMICs). Since the burden of wound infections is highest in these countries compared to other places in the world, this research proposal if timely and focussed toward a clinical need in LMICs. Wound infections are complex and testing two interventions at the same time may show even greater effect than just testing one, and it also improves value for money. The trial will be large and require around 2000 patients.  NEED FOR A DEVELOPMENT GRANT: Before we can submit a highly competitive, world-class grant proposal, we need to perform some development work to ensure that we are prepared. This work will develop a final, tangible plan for that application, and engage local doctors and research staff into the process. We aim to:  1. Hold on site meetings in participating countries, led by local surgeons, to engage a range of staff and shortlist interventions which could be tested in their units. 2. Deliver on-site research skills training that will increase local research capacity and leadership. 3. Perform small observational studies to ensure that sites have a strategy to follow-up patients during the main trial. 4. Hold our first face-to-face collaborator group meeting, to develop a finalised protocol based on the selected interventions, that can be used for a main trial application. This meeting will also allow us to foster the strongest possible relationships between our new collaborative and improve team working. NEED FOR MORE SURGICAL RESEARCH: There is a lack of surgical research across the world, partly driven by a lack of doctors regularly performing surgical research. This initial proposal will allow is to form a collaborative that could last for many decades. We predict that this network will enable us to deliver more trials into the future, of larger sizes and complexity. In the UK, we have developed hub and spoke research networks to deliver similar trials. We aim to transfer these research skills from the NHS to LMICs to help disseminate best surgical research practice widely. This will also speed recruitment to trials and maximise generalizability. We aim that this development grant and subsequent main grant will produce a generation of surgical researchers focused on testing cost-effective interventions internationally.","The Global Challenges Research Fund (GCRF) supports cutting-edge research to address challenges faced by developing countries. The fund addresses the UN sustainable development goals. It aims to maximise the impact of research and innovation to improve lives and opportunity in the developing world."],
      "participating_org_ref":["GB-GOV-13","GB-COH-RC000346","GB-COH-RC000346","GB-EDU-133784"],
      "participating_org_role":["1","2","3","4"],
      "participating_org_type":["10","15","15","80"],
      "participating_org_narrative":["DEPARTMENT FOR BUSINESS, ENERGY & INDUSTRIAL STRATEGY","MEDICAL RESEARCH COUNCIL","MEDICAL RESEARCH COUNCIL","UNIVERSITY OF BIRMINGHAM"],
      "activity_status_code":"4",
      "activity_date_iso_date":["2016-07-01T00:00:00Z","2016-09-30T00:00:00Z","2017-09-30T00:00:00Z","2017-12-29T00:00:00Z"],
      "activity_date_type":["1","2","3","4"],
      "contact_info_organisation_narrative":["Department of Business Energy and Industrial Strategy"],
      "contact_info_department_narrative":["General enquiries"],
      "contact_info_email":["enquiries@odamanagement.org"],
      "contact_info_website":["https://www.gov.uk/government/publications/beis-official-development-assistance-research-and-innovation"],
      "contact_info_mailing_address_narrative":["Department of Business, Energy and Industrial Strategy, 4th Floor, 1 Victoria Street, SW1H 0ET"],
      "activity_scope_code":"3",
      "recipient_country_code":["GT","NG","EG","GH","RW"],
      "recipient_country_percentage":[20.0,20.0,20.0,20.0,20.0],
      "sector_code":["12182"],
      "sector_vocabulary":["1"],
      "policy_marker_code":["1","5","6","7","8","10","11","12"],
      "policy_marker_significance":["0","0","0","0","0","0","0","0"],
      "policy_marker_vocabulary":["1","1","1","1","1","1","1","1"],
      "collaboration_type_code":"1",
      "default_flow_type_code":"10",
      "default_finance_type_code":"110",
      "default_aid_type_code":["D02"],
      "default_tied_status_code":"5",
      "budget_status":["1","1"],
      "budget_type":["1","1"],
      "budget_period_start_iso_date":["2016-04-01T00:00:00Z","2017-04-01T00:00:00Z"],
      "budget_period_end_iso_date":["2017-03-31T00:00:00Z","2018-03-31T00:00:00Z"],
      "budget_value":[55764.52,53674.24],
      "budget_value_currency":["GBP","GBP"],
      "capital_spend_percentage":0.0,
      "transaction_type":["3","3","3","3","3","2"],
      "transaction_date_iso_date":["2018-06-30T00:00:00Z","2017-09-30T00:00:00Z","2017-06-30T00:00:00Z","2017-03-31T00:00:00Z","2016-12-31T00:00:00Z","2016-07-01T00:00:00Z"],
      "transaction_value":[2660.38,5367.42,5367.42,5576.45,5576.45,126888.27],
      "transaction_value_currency":["GBP","GBP","GBP","GBP","GBP"],
      "transaction_value_date":["2018-06-30T00:00:00Z","2017-09-30T00:00:00Z","2017-06-30T00:00:00Z","2017-03-31T00:00:00Z","2016-12-31T00:00:00Z","2016-07-01T00:00:00Z"],
      "hierarchy":1,
      "transaction_value_usd":[3535.9991876159793,7153.734888700714,6871.194227660854,6877.665331654041,6968.401427559162,166867.00827468862]
    },{
      "default_currency":"GBP",
      "default_lang":"en",
      "iati_identifier":"GB-GOV-13-FUND--GCRF-MR_R019460_1",
      "reporting_org_ref":"GB-GOV-13",
      "reporting_org_type_code":"10",
      "reporting_org_narrative":["DEPARTMENT FOR BUSINESS, ENERGY & INDUSTRIAL STRATEGY"],
      "title_narrative":["Identifying Depression Early in Adolescence (IDEA) King's-Brazil-Nepal-Nigeria network"],
      "description_narrative":["Depression is a common mental disorder that will affect up to one out of five people around the world during their lifetimes and tends to start in adolescence. Depression is an especially debilitating mental illness because it often begins early in life and has a chronic course with many depressive episodes occurring throughout one's lifetime. Many people lack access to depression care and this is especially true in the world's poorest countries. Our proposed collaboration aims to bring a high-income country's expertise in research, where most of the scientific knowledge about depression and other mental health problems has been produced, to developing countries, where 9 out of 10 children and adolescents live. This collaboration between King's College London in the UK and researchers from Brazil, Nepal and Nigeria intends to find new ways to identify which adolescents are at risk of depression, what protects young people from developing depression, and are these factors the same or different in these contrasting contexts. Such information is crucial to help us understand how to intervene early in a range of settings to prevent a lifetime of suffering.   In order to achieve this, we propose to do the following: First, we will bring together researchers with different types of expertise from high (UK), middle (Brazil and Nigeria) and low (Nepal) income countries to reach a consensus about how to measure risk and protective factors for depression in comparable ways among adolescents in these different countries. We will then draw upon existing datasets of youth who have participated in research at multiple time points during their childhood and adolescence to run initial tests to see whether similar or different factors predict the development of depression in each country. This collaborative network will then apply for funding to conduct a new research project to assess much larger numbers of adolescents in each country with the consensus measures to identify the biological, social, psychological, and environmental factors that predict which adolescents will develop depression and which will not in each of these settings. Finally, we will scope out potential gaps in equipment, expertise, and policies in each country so that we know what needs to be put in place before such a large-scale research project can be successfully conducted. In order to begin the process of rectifying these gaps, we will deliver online training and offer hands-on apprenticeships to increase the skills of researchers in Brazil, Nepal and Nigeria to enable them to effectively conduct the research themselves.  Ultimately, this research will generate new knowledge on how to identify and prevent depression among youth, which would substantially decrease the personal, social and economic costs associated with the disorder in these countries and around the globe.","The Global Challenges Research Fund (GCRF) supports cutting-edge research to address challenges faced by developing countries. The fund addresses the UN sustainable development goals. It aims to maximise the impact of research and innovation to improve lives and opportunity in the developing world."],
      "participating_org_ref":["GB-GOV-13","GB-COH-RC000346","GB-COH-RC000346"],
      "participating_org_role":["1","2","3"],
      "participating_org_type":["10","15","15"],
      "participating_org_narrative":["DEPARTMENT FOR BUSINESS, ENERGY & INDUSTRIAL STRATEGY","MEDICAL RESEARCH COUNCIL","MEDICAL RESEARCH COUNCIL"],
      "activity_status_code":"4",
      "activity_date_iso_date":["2018-02-01T00:00:00Z","2018-02-01T00:00:00Z","2019-01-31T00:00:00Z","2019-01-31T00:00:00Z"],
      "activity_date_type":["1","2","3","4"],
      "contact_info_organisation_narrative":["Department of Business Energy and Industrial Strategy"],
      "contact_info_department_narrative":["General enquiries"],
      "contact_info_email":["enquiries@odamanagement.org"],
      "contact_info_website":["https://www.gov.uk/government/publications/beis-official-development-assistance-research-and-innovation"],
      "contact_info_mailing_address_narrative":["Department of Business, Energy and Industrial Strategy, 4th Floor, 1 Victoria Street, SW1H 0ET"],
      "activity_scope_code":"3",
      "recipient_country_code":["NP","BR","NG"],
      "recipient_country_percentage":[33.333333333333336,33.333333333333336,33.333333333333336],
      "sector_code":["12182"],
      "sector_vocabulary":["1"],
      "policy_marker_code":["1","5","6","7","8","10","11","12"],
      "policy_marker_significance":["0","0","0","0","0","0","2","0"],
      "policy_marker_vocabulary":["1","1","1","1","1","1","1","1"],
      "collaboration_type_code":"1",
      "default_flow_type_code":"10",
      "default_finance_type_code":"110",
      "default_aid_type_code":["D02"],
      "default_tied_status_code":"5",
      "budget_status":["1"],
      "budget_type":["1"],
      "budget_period_start_iso_date":["2018-04-01T00:00:00Z"],
      "budget_period_end_iso_date":["2019-03-31T00:00:00Z"],
      "budget_value":[141314.0],
      "budget_value_currency":["GBP"],
      "capital_spend_percentage":0.0,
      "transaction_type":["3","3","2"],
      "transaction_date_iso_date":["2021-09-30T00:00:00Z","2019-03-31T00:00:00Z","2018-02-01T00:00:00Z"],
      "transaction_value":[-1708.4,141314.0,141314.26],
      "transaction_value_currency":["GBP","GBP"],
      "transaction_value_date":["2021-09-30T00:00:00Z","2019-03-31T00:00:00Z","2018-02-01T00:00:00Z"],
      "hierarchy":1,
      "transaction_value_usd":[-2344.7922406041207,186111.25196740677,197408.22173174177]
    },{
      "default_currency":"GBP",
      "default_lang":"en",
      "iati_identifier":"GB-GOV-13-FUND--GCRF-MR_R019789_1",
      "reporting_org_ref":"GB-GOV-13",
      "reporting_org_type_code":"10",
      "reporting_org_narrative":["DEPARTMENT FOR BUSINESS, ENERGY & INDUSTRIAL STRATEGY"],
      "title_narrative":["Improving the survival, growth and developmental of low birth weight newborns through better nutrition"],
      "description_narrative":["Worldwide, deaths in the first month of life already account for nearly half of all child deaths. This proportion is set to rise as survival in older children is improving faster than in newborns. More than 9 in 10 newborn deaths occur in Africa and Asia and more than 8 in 10 of these deaths are in babies with low birthweight. The greatest risk is in very small babies (birthweight less than 1500g) where as many as 700 of every 1000 die. Small babies who survive often have poor longer-term growth and development posing highly significant consequences for families and societies.  Being small at birth is due mainly to being born too early (preterm), not growing well in the womb or a combination of both. Unfortunately, we do not have effective interventions to prevent either of these problems. Therefore, these small babies are a growing challenge especially in poorer countries.  We know that nutrition and growth in early life are critically important for the development of the body organs, including the brain, and being able to fight-off the infections that cause many newborn deaths. Improved nutrition and optimal growth may also prevent diseases that are important in later life in poorer countries such as lung disease. However, achieving optimal nutrition in small babies remains a huge challenge especially as high quality, safe feeding through the veins, that bridges the gap between birth and full oral feeding, is rarely available in low-resource countries. In addition, the structure and function of the gut in preterm babies is immature  and advancing oral feeds too quickly may cause life-threatening gut damage. The immature gut not only struggles to cope with milk feeds but also allows gut bacteria to cross into the body and cause infection. Small babies often need nursing in neonatal units (NNUs) for 4-6 weeks or more and this is exactly where their gut can be colonized with dangerous bacteria that are resistant to the available antibiotics.   There has been little research to tell us how best to feed small babies in NNUs in poorer countries. Even basic principles such as when to introduce feeds and how quickly feeds can be increased safely remain unclear. In addition, there are several promising interventions being developed in richer countries that may well be relevant, feasible and affordable in low-resource settings. These include using nutritional supplements of probiotics (safe, \"healthy\" bacteria) and components in breast milk (\"lactoferrin\") to prevent gut infections and boost the baby's immunity.  We will establish a core network of 6 NNUs (4 Nigeria/2 Kenya) linking African clinicians and researchers together and with international experts in newborn nutrition, gut health and longer-term lung and brain development. The network will build capacity in those NNUs with limited previous research experience and also engage researchers who are new to working in poorer countries.   Workshops in Nigeria and Kenya will allow the team to document current practices, share experience of practical feeding problems and review possible interventions for testing. Standard international criteria for the diagnosis of common problems (such as infection) will be adapted for use across the network and we will set-up a database to share essential clinical information. We will test novel methods to detect genes that make bacteria resistant to antibiotics and to measure key nutrients in small volume blood samples. We will also store samples for later research. We will ensure that we develop processes that are achievable even with low-resources so that they can be rolled-out to other NNUs to expand the network.   Our goal is to improve survival, growth and development in low birthweight babies through better nutrition. The network and processes that we will establish will enable us to design and implement the large-scale clinical trials that will be needed to advance care in these most vulnerable infants.","The Global Challenges Research Fund (GCRF) supports cutting-edge research to address challenges faced by developing countries. The fund addresses the UN sustainable development goals. It aims to maximise the impact of research and innovation to improve lives and opportunity in the developing world."],
      "participating_org_ref":["GB-GOV-13","GB-COH-RC000346","GB-COH-RC000346","GB-CHC-222655"],
      "participating_org_role":["1","2","3","4"],
      "participating_org_type":["10","15","15","80"],
      "participating_org_narrative":["DEPARTMENT FOR BUSINESS, ENERGY & INDUSTRIAL STRATEGY","MEDICAL RESEARCH COUNCIL","MEDICAL RESEARCH COUNCIL","LIVERPOOL SCHOOL OF TROPICAL MEDICINE"],
      "activity_status_code":"4",
      "activity_date_iso_date":["2018-03-01T00:00:00Z","2019-02-28T00:00:00Z","2019-02-28T00:00:00Z"],
      "activity_date_type":["1","3","4"],
      "contact_info_organisation_narrative":["Department of Business Energy and Industrial Strategy"],
      "contact_info_department_narrative":["General enquiries"],
      "contact_info_email":["enquiries@odamanagement.org"],
      "contact_info_website":["https://www.gov.uk/government/publications/beis-official-development-assistance-research-and-innovation"],
      "contact_info_mailing_address_narrative":["Department of Business, Energy and Industrial Strategy, 4th Floor, 1 Victoria Street, SW1H 0ET"],
      "activity_scope_code":"2",
      "recipient_country_code":["KE","NG"],
      "recipient_country_percentage":[50.0,50.0],
      "sector_code":["12182"],
      "sector_vocabulary":["1"],
      "policy_marker_code":["1","5","6","7","8","10","11","12"],
      "policy_marker_significance":["0","0","0","0","0","0","0","2"],
      "policy_marker_vocabulary":["1","1","1","1","1","1","1","1"],
      "collaboration_type_code":"1",
      "default_flow_type_code":"10",
      "default_finance_type_code":"110",
      "default_aid_type_code":["D02"],
      "default_tied_status_code":"5",
      "budget_status":["1"],
      "budget_type":["1"],
      "budget_period_start_iso_date":["2018-04-01T00:00:00Z"],
      "budget_period_end_iso_date":["2019-03-31T00:00:00Z"],
      "budget_value":[196947.0],
      "budget_value_currency":["GBP"],
      "capital_spend_percentage":0.0,
      "transaction_type":["3","2"],
      "transaction_date_iso_date":["2018-12-31T00:00:00Z","2018-03-01T00:00:00Z"],
      "transaction_value":[196947.0,196947.2],
      "transaction_value_currency":["GBP"],
      "transaction_value_date":["2018-12-31T00:00:00Z","2018-03-01T00:00:00Z"],
      "hierarchy":1,
      "transaction_value_usd":[249665.14769747425,275136.83489595976]
    }]
  }
}